Effect of Histone Lysine Methylation on DNA Lesion Reactivity in Nucleosome Core Particles.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.9b00049
Abstract: Lysine methylation is a common post-translational histone modification that regulates transcription and gene expression. The lysine residues in the histone tail also react with damaged nucleotides in chromatin, including abasic sites and N7-methyl-2'-deoxyguanosine, the major… read more here.
Keywords: methylation; lysine methylation; core particles; dna ... See more keywords
Structural Consequences of Deproteinating the 50S Ribosome
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DOI: 10.3390/biom12111605
Abstract: Ribosomes are complex ribonucleoprotein particles. Purified 50S ribosomes subjected to high-salt wash, removing a subset of ribosomal proteins (r-proteins), were early shown competent for in vitro assembly into functional 50S subunits. We here used cryo-EM… read more here.
Keywords: rna structure; core; structure; core particles ... See more keywords