The human RIT2 core promoter short tandem repeat predominant allele is species-specific in length: a selective advantage for human evolution?
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Genetics and Genomics"
DOI: 10.1007/s00438-017-1294-4
Abstract: Evolutionary analyses of the critical core promoter interval support a selective advantage for expanding the length of certain short tandem repeats (STRs) in humans. We recently reported genome-wide data on human core promoter STRs that… read more here.
Keywords: allele; core promoter; repeat; selective advantage ... See more keywords
Delineation of the DNA Structural Features of Eukaryotic Core Promoter Classes
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c04603
Abstract: The eukaryotic transcription is orchestrated from a chunk of the DNA region stated as the core promoter. Multifarious and punctilious core promoter signals, viz., TATA-box, Inr, BREs, and Pause Button, are associated with a subset… read more here.
Keywords: promoter; dna structural; core promoter; promoter classes ... See more keywords
The global regulator Ncb2 escapes from the core promoter and impacts transcription in response to drug stress in Candida albicans
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep46084
Abstract: Ncb2, the β subunit of NC2 complex, a heterodimeric regulator of transcription was earlier shown to be involved in the activated transcription of CDR1 gene in azole resistant isolate (AR) of Candida albicans. This study… read more here.
Keywords: response drug; drug; core promoter; candida albicans ... See more keywords
35 Characterization of the promoter region of ZNFO, an oocyte-specific gene in cattle
Sign Up to like & getrecommendations! Published in 2021 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv33n2ab35
Abstract: Maternal factors are essential aspects of oocyte competence, which orchestrate early embryonic development. ZNFO is a Kruppel-associated box domain (KRAB) containing zinc finger transcription factor, which is exclusively expressed in bovine oocyte. Previous studies have… read more here.
Keywords: core promoter; promoter region; transcription; promoter ... See more keywords
Sp1 Controls the Basal Level of Interleukin-34 Transcription
Sign Up to like & getrecommendations! Published in 2022 at "Immunological Investigations"
DOI: 10.1080/08820139.2022.2157283
Abstract: ABSTRACT Interleukin-34 (IL-34) is a cytokine that plays important roles at steady state and in diseases. The induced or inhibited expression of IL-34 by stimuli has been deeply investigated. However, the regulation of IL-34 basal… read more here.
Keywords: core promoter; transcription; expression; sp1 controls ... See more keywords
Clinical features of hepatitis B patients at immune‐tolerance phase with basal core promoter and/or precore mutations
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13315
Abstract: Little data exist on basal core promoter/precore (BCP/PC) mutations in chronic hepatitis B (CHB) patients at the immune‐tolerance (IT) phase. We studied consecutive treatment‐naïve, CHBe‐antigen (HBeAg)‐positive patients who had undergone liver biopsy and genotyping. Those… read more here.
Keywords: phase; patients immune; core promoter; promoter precore ... See more keywords
Distinct core promoter codes drive transcription initiation at key developmental transitions in a marine chordate
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-4504-5
Abstract: BackgroundDevelopment is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component of this and yet few rules governing selection are known. Here, we… read more here.
Keywords: transcription; promoter codes; core promoter; promoter ... See more keywords
Control of human gene expression: High abundance of divergent transcription in genes containing both INR and BRE elements in the core promoter
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202927
Abstract: Background DNA sequence elements in the core promoter can play a central role in regulation of gene expression. Core elements (e.g. INR and TATA box) are located within ~50bp of the transcription start site and… read more here.
Keywords: gene expression; core promoter; bre elements; promoter ... See more keywords
Identification of evolutionarily conserved downstream core promoter elements required for the transcriptional regulation of Fushi tarazu target genes
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0215695
Abstract: The regulation of transcription initiation is critical for developmental and cellular processes. RNA polymerase II (Pol II) is recruited by the basal transcription machinery to the core promoter where Pol II initiates transcription. The core… read more here.
Keywords: core promoter; downstream core; transcription; promoter ... See more keywords
The Molecular Characteristics of the FAM13A Gene and the Role of Transcription Factors ACSL1 and ASCL2 in Its Core Promoter Region
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10120981
Abstract: The gene family with sequence similarity 13 member A (FAM13A) has recently been identified as a marker gene in insulin sensitivity and lipolysis. In this study, we first analyzed the expression patterns of this gene… read more here.
Keywords: promoter region; acsl1 ascl2; core promoter; gene ... See more keywords
Identification of the Core Promoter and Variants Regulating Chicken CCKAR Expression
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13061083
Abstract: Decreased expression of chicken cholecystokinin A receptor (CCKAR) attenuates satiety, which contributes to increased food intake and growth for modern broilers. The study aims to define the core promoter of CCKAR, and to identify variants… read more here.
Keywords: cckar; core promoter; growth; expression ... See more keywords