Eukaryotic core promoters and the functional basis of transcription initiation
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Molecular Cell Biology"
DOI: 10.1038/s41580-018-0028-8
Abstract: RNA polymerase II (Pol II) core promoters are specialized DNA sequences at transcription start sites of protein-coding and non-coding genes that support the assembly of the transcription machinery and transcription initiation. They enable the highly… read more here.
Keywords: transcription; gene; transcription initiation; core promoters ... See more keywords
High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity.
Sign Up to like & getrecommendations! Published in 2019 at "Genome research"
DOI: 10.1101/gr.242222.118
Abstract: Transcription initiates at both coding and noncoding genomic elements, including mRNA and long noncoding RNA (lncRNA) core promoters and enhancer RNAs (eRNAs). However, each class has a different expression profile with lncRNAs and eRNAs being… read more here.
Keywords: lncrna core; tissue specificity; tissue; core promoters ... See more keywords
Pervasive and dynamic transcription initiation in Saccharomyces cerevisiae.
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DOI: 10.1101/gr.245456.118
Abstract: Transcription initiation is finely regulated to ensure proper expression and function of genes. The regulated transcription initiation in response to various environmental stimuli in a classic model organism Saccharomyces cerevisiae has not been systematically investigated.… read more here.
Keywords: transcription; saccharomyces cerevisiae; transcription initiation; core promoters ... See more keywords
Selective translational usage of TSS and core promoters revealed by translatome sequencing
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-5650-0
Abstract: BackgroundIn mammals, fine-tuned regulation of gene expression leads to transcription initiation from diverse transcription start sites (TSSs) and multiple core promoters. Although polysome association is a critical step in translation, whether polysome selectively uses TSSs… read more here.
Keywords: translation; core promoters; usage; transcription initiation ... See more keywords