A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation.
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DOI: 10.1182/blood.2022015708
Abstract: Clinically tolerable, permissive HLA-DPB1 mismatches defined by the T-cell epitope (TCE) model improve the selection of unrelated donors in allogeneic hematopoietic cell transplantation (HCT). Mechanistically, overlapping immunopeptidomes in structurally close HLA-DP allotypes with similar peptide-binding… read more here.
Keywords: hla dpb1; dpb1 alleles; core; core tce3 ... See more keywords