Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12923
Abstract: The epigenomic regulation of transcriptional programs in metastatic prostate cancer is poorly understood. We studied the epigenomic landscape of prostate cancer drivers using transcriptional profiling and ChIP‐seq in four clonal metastatic tumors derived from a… read more here.
Keywords: prostate; core transcriptional; prostate cancer; transcriptional program ... See more keywords
Core transcriptional regulatory circuitries in cancer
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01459-w
Abstract: Transcription factors (TFs) coordinate the on-and-off states of gene expression typically in a combinatorial fashion. Studies from embryonic stem cells and other cell types have revealed that a clique of self-regulated core TFs control cell… read more here.
Keywords: core tfs; transcriptional regulatory; core transcriptional; regulatory circuitries ... See more keywords