Phorbolester-activated Munc13-1 and ubMunc13-2 exert opposing effects on dense-core vesicle secretion
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DOI: 10.7554/elife.79433
Abstract: Munc13 proteins are priming factors for SNARE-dependent exocytosis, which are activated by diacylglycerol (DAG)-binding to their C1-domain. Several Munc13 paralogs exist, but their differential roles are not well understood. We studied the interdependence of phorbolesters… read more here.
Keywords: munc13; munc13 ubmunc13; core vesicle; secretion ... See more keywords