A Coreceptor-Mimetic Peptide Enhances the Potency of V3-Glycan Antibodies
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DOI: 10.1128/jvi.01653-18
Abstract: HIV-1 requires both the cellular receptor CD4 and a tyrosine-sulfated coreceptor to infect its target cells. CD4-Ig is a fusion of the HIV-1-binding domains of CD4 with an antibody Fc domain. Previous studies have demonstrated… read more here.
Keywords: coreceptor mimetic; potency; coreceptor; sulfopeptide ... See more keywords