Corin is a key regulator of endochondral ossification and bone development via modulation of vascular endothelial growth factor A expression
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2760
Abstract: Corin has been studied extensively within the vascular system and is known to regulate blood pressure. We have shown that corin is one of the most highly upregulated genes during osteogenic differentiation of human adipose‐derived… read more here.
Keywords: medicine; corin; bone; expression ... See more keywords
Corin is highly expressed in atherosclerosis models.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.08.173
Abstract: Corin is a serine protease mainly expressed in the heart, where it regulates blood pressure and cardiac function through activating pro-atrial natriuretic peptide (pro-ANP) to ANP. Its expression has also been detected in non-cardiac tissues.… read more here.
Keywords: corin highly; corin; highly expressed; expression ... See more keywords
Association of rs2271037 and rs3749585 polymorphisms in CORIN with susceptibility to hypertension in a Chinese Han population: A case-control study.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.01.080
Abstract: Corins are membrane-bound protease that regulates blood pressure by activating the natriuretic peptides. These pro-atrial natriuretic peptide convertases are essential for sodium homeostasis and normal blood pressure. CORIN variants have been identified in humans and… read more here.
Keywords: rs3749585; susceptibility; study; corin ... See more keywords
Aberrant corin and PCSK6 in placentas of the maternal hyperinsulinemia IUGR rat model.
Sign Up to like & getrecommendations! Published in 2020 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2020.05.007
Abstract: OBJECTIVES Corin is a protease that converts pro-atrial natriuretic peptide (pro-ANP) to ANP. While the involvement of ANP in the cardiovascular regulation is well established, there is increasing evidence that the pregnant uterus produces ANP,… read more here.
Keywords: aberrant corin; pcsk6 placentas; corin; placentas maternal ... See more keywords
Function and regulation of corin in physiology and disease.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical Society transactions"
DOI: 10.1042/bst20190760
Abstract: Atrial natriuretic peptide (ANP) is of major importance in the maintenance of electrolyte balance and normal blood pressure. Reduced plasma ANP levels are associated with the increased risk of cardiovascular disease. Corin is a type… read more here.
Keywords: physiology; function regulation; physiology disease; corin ... See more keywords
Siberian cats help in solving part of the mystery surrounding golden cats.
Sign Up to like & getrecommendations! Published in 2021 at "Animal genetics"
DOI: 10.1111/age.13076
Abstract: Golden cats have been appreciated since the beginning of the cat fancy. Golden is a modification of the tabby coat. In the Siberian breed, a specific golden phenotype, named sunshine, has been described. Sunshine tabby… read more here.
Keywords: siberian cats; corin; corin 2383c; tabby ... See more keywords
Golden cats: A never‐ending story!
Sign Up to like & getrecommendations! Published in 2022 at "Animal Genetics"
DOI: 10.1111/age.13228
Abstract: Abstract In the British feline breed a golden coat modification, called light‐gold, akita or copper, was reported by breeders during the 2010s. This modification restricted eumelanin to the tip of the tail and hairs showed… read more here.
Keywords: never ending; golden cats; cats never; corin ... See more keywords
Association between CORIN methylation and hypertension in Chinese adults.
Sign Up to like & getrecommendations! Published in 2022 at "Postgraduate medical journal"
DOI: 10.1136/pmj-2022-141802
Abstract: BACKGROUND Corin, a physical activator of atrial natriuretic peptide, has been associated with hypertension with unclear mechanisms. Here, we aimed to examine whether CORIN gene methylation was involved in the underlying molecular mechanisms. METHODS DNA… read more here.
Keywords: methylation; hypertension; association corin; corin ... See more keywords
Associations between potentially functional CORIN SNPs and serum corin levels in the Chinese Han population
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genetics"
DOI: 10.1186/s12863-019-0802-4
Abstract: BackgroundCorin is an important convertase involved in the natriuretic peptide system and may indirectly regulate blood pressure. Genetic factors relate to corin remain unclear. The purpose of the current study was to comprehensively examine the… read more here.
Keywords: potentially functional; corin levels; corin; serum corin ... See more keywords
Natriuretic peptides system in the pulmonary tissue of rats with heart failure: potential involvement in lung edema and inflammation
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24922
Abstract: Congestive heart failure (CHF) often leads to progressive cardiac hypertrophy and salt/water retention as evident by peripheral and lung edema. Although the pathogenesis of CHF remains largely unclarified, it is widely accepted that neurohormonal changes… read more here.
Keywords: pulmonary tissue; heart failure; corin;
Corin: A Key Mediator in Sodium Homeostasis, Vascular Remodeling, and Heart Failure
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11050717
Abstract: Simple Summary Atrial natriuretic peptide (ANP) is an important hormone that regulates many physiological and pathological processes, including electrolyte and body fluid balance, blood volume and pressure, cardiac channel activity and function, inflammatory response, lipid… read more here.
Keywords: heart failure; vascular remodeling; heart; corin ... See more keywords