Overcoming the Stromal Barrier of the Cornea with a Peptide Conjugate Nano‐Assembly to Combat Fungal Keratitis
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202202409
Abstract: Fungal hyphae deeply invade the cornea in fungal keratitis. The corneal stroma hinders the infiltration of antifungal drugs and reduces their bioavailability. Here, this work reports a peptide conjugate nano‐assembly that permeates the stroma and… read more here.
Keywords: fungal keratitis; cornea; nano; nano assembly ... See more keywords
Gradients of Orientation, Composition, and Hydration of Proteins for Efficient Light Collection by the Cornea of the Horseshoe Crab
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203371
Abstract: The lateral eyes of the horseshoe crab, Limulus polyphemus, are the largest compound eyes within recent Arthropoda. While this visual system has been extensively described before, the precise mechanism allowing vision has remained controversial. Correlating… read more here.
Keywords: hydration; light collection; composition; cornea ... See more keywords
To prepare the collagen‐based artificial cornea with improved mechanical and biological property by ultraviolet‐A/riboflavin crosslinking
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45226
Abstract: In the present study, we optimized the ultraviolet-A (UVA)/riboflavin crosslinking for the collagen-based artificial cornea for the first time to resolve the lack of donor cornea for corneal disease. We found that the crosslinking conditions,… read more here.
Keywords: riboflavin crosslinking; based artificial; cornea; collagen based ... See more keywords
Optical coherence elastography for strain dynamics measurements in laser correction of cornea shape.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biophotonics"
DOI: 10.1002/jbio.201600291
Abstract: We describe the use of elastographic processing in phase-sensitive optical coherence tomography (OCT) for visualizing dynamics of strain and tissue-shape changes during laser-induced photothermal corneal reshaping, for applications in the emerging field of non-destructive and… read more here.
Keywords: optical coherence; phase; shape; cornea ... See more keywords
Dynamic development of the extracellular matrix in chick cornea
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202100210
Abstract: Understanding the mechanisms of structural organization of corneal stroma is scientifically interesting and may lead to advances in corneal tissue engineering. In the past, we used the combination of second harmonic generation and fast Fourier… read more here.
Keywords: extracellular matrix; development; dynamic development; cornea ... See more keywords
Novel Acoustic radiation force optical coherence elastography based on ultrasmall ultrasound transducer for biomechanics evaluation of in vivo cornea.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300074
Abstract: We developed a novel acoustic radiation force optical coherence elastography (ARF-OCE) based on an ultrasmall ultrasound transducer for quantitative biomechanics evaluations of in vivo cornea. A custom single-sided meta-ultrasonic transducer with an outer diameter of… read more here.
Keywords: transducer; novel acoustic; cornea; radiation force ... See more keywords
The functional anatomy of the cornea of the Shorthead lamprey, Mordacia mordax (Mordaciidae, Agnatha): A comparison between downstream and upstream migrants
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Morphology"
DOI: 10.1002/jmor.21552
Abstract: The Shorthead lamprey Mordacia mordax (Mordaciidae, Agnatha) represents one of the earliest stages of vertebrate evolution. This study investigates the ultrastructural anatomy of the cornea, iris and anterior chamber in the eyes of this species… read more here.
Keywords: lamprey mordacia; mordacia mordax; cornea; mordax mordaciidae ... See more keywords
Successful development and clinical translation of a novel anterior lamellar artificial cornea
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2951
Abstract: Blindness due to corneal diseases is a common pathology affecting up to 23 million individuals worldwide. The tissue‐engineered anterior human cornea, which is currently being tested in a Phase I/II clinical trial to treat severe… read more here.
Keywords: development clinical; cornea; successful development; translation ... See more keywords
The Self-assembly Approach as a Tool for the Tissue Engineering of a Bi-lamellar Human Cornea.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0599-8_8
Abstract: Tissue engineering is a flourishing field of regenerative medicine that allows the reconstruction of various tissues of our body, including the cornea. In addition to addressing the growing need for organ transplants, such tissue-engineered substitutes… read more here.
Keywords: human corneal; cornea; tissue engineering; tissue ... See more keywords
Corneal reconstruction in chemically damaged cornea using temperature responsive surface assisted mesenchymal stem cell transplantation in rabbits
Sign Up to like & getrecommendations! Published in 2021 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-021-05132-0
Abstract: Transplantation of autologous stem cells over damaged cornea seems to be a promising approach for corneal reconstruction. Use of a biocompatible carrier is still a challenge in bedside translation of transplantation. We investigated corneal reconstruction… read more here.
Keywords: corneal reconstruction; using temperature; temperature responsive; cornea ... See more keywords
Numerical and Experimental Study of the Spatial Stress Distribution on the Cornea Surface During a Non-Contact Tonometry Examination
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Mechanics"
DOI: 10.1007/s11340-018-00449-0
Abstract: The determination of biomechanical properties of the cornea by a non-contact tonometry (NCT) examination requires a precise knowledge of the air puff generated in the device, which is applied to the cornea surface. In this… read more here.
Keywords: contact tonometry; examination; cornea; study ... See more keywords