Subconjunctival administration of mesenchymal stem cells alleviates ocular inflammation in a murine model of corneal alkali burn.
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DOI: 10.1093/stmcls/sxad027
Abstract: Corneal alkali burns cause extensive damage not only on the cornea but also into the intraocular tissues. As an anti-inflammatory therapy, subconjunctival administration of mesenchymal stem cells (MSCs) for corneal protection after corneal alkali burn… read more here.
Keywords: burn; subconjunctival administration; corneal alkali; mscs ... See more keywords
The Wound Healing Effect of Doxycycline after Corneal Alkali Burn in Rats
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DOI: 10.1155/2019/5168652
Abstract: Purpose To evaluate the wound healing effect of doxycycline and its underlying mechanisms in a rat model of corneal alkali burn. Methods Male SD rats were administered 1.0 N NaOH in the right cornea for 25… read more here.
Keywords: wound healing; corneal alkali; group; alkali burn ... See more keywords
The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns
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DOI: 10.1155/2020/7485912
Abstract: Objective To investigate therapeutic effects and possible mechanism of pranoprofen in a mouse model of corneal alkali burns and provide new evidence for the clinical treatment of corneal alkali burns. Methods A unilateral alkali burn… read more here.
Keywords: saline group; corneal; alkali burns; corneal alkali ... See more keywords
Evaluation of Clinical and Histological Outcomes of Adipose-Derived Mesenchymal Stem Cells in a Rabbit Corneal Alkali Burn Model
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DOI: 10.1155/2021/6610023
Abstract: To assess effects of adipose-derived mesenchymal stem cells (AMSCs) in corneal alkali injuries in an experimental animal model. Twenty white New Zealand rabbits were included in the study. The animal models were randomly divided into… read more here.
Keywords: derived mesenchymal; corneal alkali; group; stem cells ... See more keywords
Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice
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DOI: 10.3390/pharmaceutics14020316
Abstract: Corneal chemical burns (CCBs) frequently result in corneal fibrosis or haze, an opacity of the cornea that obstructs vision and induces corneal blindness. Diverse strategies have been employed to prevent or reduce CCB-related corneal haze.… read more here.
Keywords: formulation; corneal alkali; topical pirfenidone; corneal ... See more keywords