Theranostic‐guided corneal cross‐linking: Preclinical evidence on a new treatment paradigm for keratoconus
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biophotonics"
DOI: 10.1002/jbio.202200218
Abstract: Theranostics is an emerging therapeutic paradigm of personalized medicine; the term refers to the simultaneous integration of therapy and diagnostics. In this work, theranostic‐guided corneal cross‐linking was performed on 10 human sclero‐corneal tissues. The samples… read more here.
Keywords: theranostic guided; corneal cross; cross linking; corneal ... See more keywords
First experience with Oasis Collagen SOFT SHIELD® for epithelial defect after corneal cross-linking
Sign Up to like & getrecommendations! Published in 2019 at "International Ophthalmology"
DOI: 10.1007/s10792-018-01070-9
Abstract: BackgroundTo investigate response of dissolving collagen contact lenses as an alternative for bandage contact lenses, for the post-interventional care of epithelial defects after corneal cross-linking (CXL) treatment for keratoconus.Patients and methodsFollow-up visits were performed at… read more here.
Keywords: soft shield; collagen soft; cross linking; day ... See more keywords
Pediatric Corneal Cross-linking: Comparison of Visual and Topographic Outcomes Between Conventional and Accelerated Treatment.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2017.08.015
Abstract: PURPOSE To compare visual and topographic outcomes 1 year after conventional (C-CXL) vs accelerated corneal cross-linking (A-CXL) in pediatric keratoconus (KC). DESIGN Comparative, retrospective, consecutive case series. METHODS Patients with topography-confirmed, progressive KC and a… read more here.
Keywords: visual topographic; treatment; topographic outcomes; cxl ... See more keywords
Individualized corneal cross-linking with riboflavin and UV-A in ultra-thin corneas: the sub400 protocol.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2020.12.011
Abstract: PURPOSE To determine whether corneal cross-linking with individualized fluence ("sub400 protocol") is able to stop keratoconus progression in ultra-thin corneas with 12-month follow-up. DESIGN Retrospective, interventional case series. METHODS Thirty-nine eyes with progressive keratoconus and… read more here.
Keywords: sub400 protocol; thin corneas; ultra thin; cross linking ... See more keywords
Re: Kontadakis et al.: Long-term comparison of simultaneous topography-guided photorefractive keratectomy followed by corneal cross-linking versus corneal cross-linking alone (Ophthalmology. 2016;123:974-983).
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2016.06.067
Abstract: discussed in our manuscript. The quantitative angle parameters measured by anterior segment optical coherence tomography found some angle widening in iridoplasty eyes, but this did not translate into effective gonioscopic widening. By effective, we mean… read more here.
Keywords: topography; long term; ophthalmology; cross linking ... See more keywords
Randomized Controlled Trial Comparing Transepithelial Corneal Cross-linking Using Iontophoresis with the Dresden Protocol in Progressive Keratoconus.
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2017.01.040
Abstract: PURPOSE To compare clinical outcomes of transepithelial corneal cross-linking using iontophoresis (T-ionto CL) and standard corneal cross-linking (standard CL) for the treatment of progressive keratoconus 12 months after the operation. DESIGN Prospective randomized controlled clinical… read more here.
Keywords: corneal; using iontophoresis; dresden protocol; progressive keratoconus ... See more keywords
Statistical Evaluation of Correlated Measurement Data in Longitudinal Setting Based on Bilateral Corneal Cross-Linking
Sign Up to like & getrecommendations! Published in 2022 at "Current Eye Research"
DOI: 10.1080/02713683.2022.2052105
Abstract: Abstract Purpose In ophthalmology, data from both eyes of a person are frequently included in the statistical evaluation. This violates the requirement of data independence for classical statistical tests (e.g. t-Test or analysis of variance… read more here.
Keywords: statistical evaluation; corneal cross; evaluation; cross linking ... See more keywords
Corneal Cross-Linking: An Effective Treatment Option for Pellucid Marginal Degeneration
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in Ophthalmology"
DOI: 10.1080/08820538.2019.1659832
Abstract: ABSTRACT Purpose: This is the first review article examining literature specific to the use of corneal cross-linking (CXL) to treat pellucid marginal degeneration (PMD). Results: CXL appears to be an effective treatment that may halt… read more here.
Keywords: effective treatment; marginal degeneration; cross linking; pellucid marginal ... See more keywords
Customised Peripheral Corneal Cross-linking (P-CXL) for Ultra-thin Corneas with Stage III and IV Keratoconus.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in ophthalmology"
DOI: 10.1080/08820538.2023.2179407
Abstract: PURPOSE This study aims to determine whether customised peripheral corneal cross-linking (P-CXL) can halt keratoconus progression in ultrathin corneas with stage 3 and 4 keratoconus, with thinnest pachymetry well below 400 μm and therefore excluded from… read more here.
Keywords: peripheral corneal; corneal cross; cross linking; linking cxl ... See more keywords
Corneal cross-linking versus conventional management for keratoconus: a lifetime economic model.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medical economics"
DOI: 10.1080/13696998.2020.1851556
Abstract: AIMS Assess the cost-effectiveness of corneal collagen cross-linking (CXL) versus no CXL for keratoconus in the United States (US). METHODS A discrete-event microsimulation was developed to assess the cost-effectiveness of corneal cross-linking (CXL, Photrexa + KXL combination… read more here.
Keywords: cxl; cross; cross linking; cost ... See more keywords
Evaluation of Dynamic Corneal Response Parameters and the Biomechanical E-Staging After Accelerated Corneal Cross-Linking in Keratoconus
Sign Up to like & getrecommendations! Published in 2022 at "Asia-Pacific Journal of Ophthalmology"
DOI: 10.1097/apo.0000000000000580
Abstract: Purpose: This study evaluated the biomechanical E-staging in progressive keratoconus (KC) corneas before and after epithelium-off accelerated corneal cross-linking (CXL, 9 mW/cm2, 10 min, 5.4 J/cm2). Design: German university-based retrospective longitudinal cohort study. Methods: The… read more here.
Keywords: biomechanical staging; cross linking; accelerated corneal; corneal cross ... See more keywords