PACAP through EGFR transactivation preserves human corneal endothelial integrity
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28293
Abstract: The corneal endothelium is composed of a single hexagonal‐shaped cells layer adherent to the Descemet's membrane. The primary function of these cells is maintaining of tissue clarity by regulating its hydration. Trauma, aging or other… read more here.
Keywords: pacap; corneal endothelial; egfr transactivation; endothelial integrity ... See more keywords
Translational issues for human corneal endothelial tissue engineering
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2131
Abstract: Corneal endothelial disorders collectively represent a significant healthcare burden in most developed nations, and corneal transplantation is currently the only treatment available for patients with poor visual acuity and corneal blindness secondary to endothelial failure.… read more here.
Keywords: human corneal; corneal endothelial; translational issues; tissue engineering ... See more keywords
Potential of a novel scaffold composed of human platelet lysate and fibrin for human corneal endothelial cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue banking"
DOI: 10.1007/s10561-021-09931-x
Abstract: Cell-based therapies have been emerged to find innovative solutions for corneal endothelial dysfunction. The aim of this study is to investigate the suitability of a blended scaffold containing human platelet lysate (HPL) and fibrin not… read more here.
Keywords: hpl fibrin; scaffold; corneal endothelial; fibrin ... See more keywords
Corneal Endothelial Transplantation in Uveitis: Incidence and Risk Factors.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.10.031
Abstract: PURPOSE To estimate the incidence of corneal endothelial transplantation and identify risk factors among patients with non-infectious ocular inflammation. DESIGN Retrospective cohort study. METHODS Adult patients attending United States tertiary uveitis care facilities diagnosed with… read more here.
Keywords: incidence; corneal endothelial; risk factors; endothelial transplantation ... See more keywords
Corneal endothelial dysfunction caused by Asclepias curassavica in a young farmer
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2019.100564
Abstract: Purpose To introduce a case of corneal endothelial toxicity caused by Asclepias curassavica (Milkweed) in Korea. Observations A 37-year-old Asian man presented with decreased vision and redness in the right eye, which developed after contact… read more here.
Keywords: corneal; caused asclepias; corneal edema; corneal endothelial ... See more keywords
Expansion and cryopreservation of porcine and human corneal endothelial cells.
Sign Up to like & getrecommendations! Published in 2017 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2017.04.012
Abstract: Impairment of the corneal endothelium causes blindness that afflicts millions worldwide and constitutes the most often cited indication for corneal transplants. The scarcity of donor corneas has prompted the alternative use of tissue-engineered grafts which… read more here.
Keywords: expansion cryopreservation; corneal endothelial; corneal; endothelial cells ... See more keywords
Near infra‐red light attenuates corneal endothelial cell dysfunction in situ and in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2017.06.008
Abstract: ABSTRACT In the present study mechanical damage to the corneal endothelium was induced by elevation of intraocular pressure (IOP, 140 mmHg, 60 min) to one eye of rats, delivered either in complete darkness or in… read more here.
Keywords: corneal endothelial; corneal endothelium; red light; light ... See more keywords
Investigating the effect of chitosan/ polycaprolactone blends in differentiation of corneal endothelial cells and extracellular matrix compositions.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.05.019
Abstract: This study aimed to investigate the underlying mechanisms of corneal endothelial cells (CECs) differentiation and identify the extracellular matrix (ECM) compositions using chitosan/polycaprolactone (PCL) blended membrane, hence exploring the potential use of chitosan/PCL blends in… read more here.
Keywords: extracellular matrix; corneal endothelial; chitosan polycaprolactone; differentiation ... See more keywords
Hyperglycemia induces corneal endothelial dysfunction through attenuating mitophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108903
Abstract: Hyperglycemia increases the risk of corneal endothelial dysfunction, resulting in damage to corneal endothelial structure and function. However, the effect and mechanism of hyperglycemia-induced corneal endothelial damage remain elusive. In this study, we demonstrated that… read more here.
Keywords: hyperglycemia; hyperglycemia induces; endothelial dysfunction; induces corneal ... See more keywords
Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Redox Biology"
DOI: 10.1016/j.redox.2019.101417
Abstract: Corneal transparency is maintained by a monolayer of corneal endothelial cells. Defects in corneal endothelial cells (CEnCs) can be rectified surgically through transplantation. Fuchs’ endothelial corneal dystrophy (FECD) is the foremost cause of endothelial dysfunction… read more here.
Keywords: corneal endothelial; lipid peroxidation; peroxidation; regulates lipid ... See more keywords
Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09304-9
Abstract: The corneal endothelium is vital for transparency and proper hydration of the cornea. Here, we conduct a genome-wide association study of corneal endothelial cell density (cells/mm2), coefficient of cell size variation (CV), percentage of hexagonal… read more here.
Keywords: cell density; corneal endothelial; cell; endothelial cell ... See more keywords