Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203257
Abstract: Nanoneedles can target nucleic acid transfection to primary cells at tissue interfaces with high efficiency and minimal perturbation. The corneal endothelium is an ideal target for nanoneedle‐mediated RNA interference therapy aimed at enhancing its proliferative… read more here.
Keywords: corneal endothelium; human corneal; corneal; nanoneedles induce ... See more keywords
The effect of combined phacotrabeculectomy, trabeculectomy and phacoemulsification on the corneal endothelium in the early stage: a preliminary study
Sign Up to like & getrecommendations! Published in 2018 at "International Ophthalmology"
DOI: 10.1007/s10792-018-1044-6
Abstract: PurposeWe aimed to investigate the effect of combined phacotrabeculectomy, trabeculectomy and phacoemulsification on the corneal endothelium in the early stage.Materials and methodsIn this prospective and non-randomized study, three groups were identified each consisting of 20… read more here.
Keywords: corneal endothelium; group; phacoemulsification; three groups ... See more keywords
Lack of association between obstructive sleep apnea syndrome and specular microscopic features of the corneal endothelium
Sign Up to like & getrecommendations! Published in 2020 at "Sleep and Breathing"
DOI: 10.1007/s11325-020-02222-x
Abstract: Obstructive sleep apnea syndrome (OSAS) is characterized by recurrent episodes of hypoxemia and hypercapnia during sleep. The aim of this study was to determine whether OSAS causes significant changes in corneal endothelium detectable by specular… read more here.
Keywords: microscopy; corneal endothelium; group; osas group ... See more keywords
Corneal Endothelium:A Promising Quantitative Index for Graves Ophthalmopathy Activity Evaluation.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.05.020
Abstract: PURPOSE To investigate the corneal endothelium damage in Graves ophthalmopathy (GO) and its role as a promising quantitative index to evaluate GO activity. DESIGN Cross-sectional study. METHODS This study included 128 eyes of 64 patients… read more here.
Keywords: corneal endothelium; activity; endothelium; quantitative index ... See more keywords
Near infra‐red light attenuates corneal endothelial cell dysfunction in situ and in vitro
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2017.06.008
Abstract: ABSTRACT In the present study mechanical damage to the corneal endothelium was induced by elevation of intraocular pressure (IOP, 140 mmHg, 60 min) to one eye of rats, delivered either in complete darkness or in… read more here.
Keywords: corneal endothelial; corneal endothelium; red light; light ... See more keywords
Physiological pressure enhances the formation of tight junctions in engineered and native corneal endothelium.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2018.11.004
Abstract: Cells and tissues are influenced by environmental conditions. In vivo, the corneal endothelium is subjected to hydrostatic intraocular pressure (IOP) and to the hydrokinetic pressure of the moving aqueous humor in the anterior chamber. In… read more here.
Keywords: endothelium; corneal endothelium; tight junctions; formation tight ... See more keywords
Periocular neural crest cell differentiation into corneal endothelium is influenced by signals in the nascent corneal environment.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental biology"
DOI: 10.1016/j.ydbio.2020.06.012
Abstract: During ocular development, periocular neural crest cells (pNC) migrate into the region between the lens and presumptive corneal epithelium to form the corneal endothelium and stromal keratocytes. Although defects in neural crest cell development are… read more here.
Keywords: corneal; corneal endothelium; differentiation; neural crest ... See more keywords
Regeneration of the Corneal Endothelium
Sign Up to like & getrecommendations! Published in 2019 at "Current Eye Research"
DOI: 10.1080/02713683.2019.1700529
Abstract: ABSTRACT Penetrating keratoplasty was the only therapeutic choice for the treatment of corneal endothelial decompensation until the introduction of evolutional endothelial keratoplasties, namely Descemet’s stripping automated endothelial keratoplasty (DSAEK) and Descemet’s membrane endothelial keratoplasty (DMEK).… read more here.
Keywords: corneal; corneal endothelial; regeneration; corneal endothelium ... See more keywords
Imaging the Corneal Endothelium in Fuchs Corneal Endothelial Dystrophy
Sign Up to like & getrecommendations! Published in 2019 at "Seminars in Ophthalmology"
DOI: 10.1080/08820538.2019.1632355
Abstract: ABSTRACT Fuchs endothelial corneal dystrophy (FECD) is characterized by the progressive degeneration of the corneal endothelium (CE). The purpose of this article is to review the diagnostic tools available to image and assess the CE… read more here.
Keywords: microscopy; corneal endothelium; dystrophy; endothelium fuchs ... See more keywords
Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma
Sign Up to like & getrecommendations! Published in 2017 at "Human Molecular Genetics"
DOI: 10.1093/hmg/ddx028
Abstract: Abstract Intraocular pressure (IOP) is maintained as a result of the balance between production of aqueous humour (AH) by the ciliary processes and hydrodynamic resistance to its outflow through the conventional outflow pathway comprising the… read more here.
Keywords: aav mediated; corneal endothelium; mmp; glaucoma ... See more keywords
Analysis of Immune Cells on Donor Corneal Endothelium After Corneal Transplantation Using the HRT-Rostock Cornea Module
Sign Up to like & getrecommendations! Published in 2021 at "Cornea"
DOI: 10.1097/ico.0000000000002706
Abstract: Supplemental Digital Content is Available in the Text. Purpose: The aim of this study was to investigate the immune cells on corneal endothelium of the graft in patients who underwent penetrating keratoplasty (PK), Descemet-stripping endothelial… read more here.
Keywords: corneal endothelium; microscopy; cells corneal; immune cells ... See more keywords