Phosphoprotein network analysis of corneal epithelium of keratoconus patients
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202100416
Abstract: Keratoconus (KC) is non‐inflammatory, bilateral progressive corneal ectasia, and a disease of established biomechanical instability. The etiology of KC is believed to be multifactorial. Although previous studies gained insight into the understanding of the disease,… read more here.
Keywords: corneal epithelium; keratoconus; corneal; analysis corneal ... See more keywords
Keeping an eye on Ca2+ signalling to tackle dry eye diseases
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103741
Abstract: Fig. 1. Loss of CISD2 appears to be an important aspect in the pathogenesis of corneal An early consequence of ageing in humans is a decline in vision. Usually, this is limited to presbyopia starting… read more here.
Keywords: cisd2; corneal epithelium; eye; keeping eye ... See more keywords
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18480-x
Abstract: Keratoconus is a common degenerative corneal disease that can lead to significant visual morbidity, and both genetic and environmental factors have been implicated in its pathogenesis. We compared the transcriptome of keratoconus and control epithelium… read more here.
Keywords: corneal; corneal epithelium; keratoconus myopia; rna seq ... See more keywords
Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32410-5
Abstract: Type 2 diabetes mellitus is characterized by a low-grade inflammation; however, mechanisms leading to this inflammation in specific tissues are not well understood. The eye can be affected by diabetes; thus, we hypothesized that inflammatory… read more here.
Keywords: corneal epithelium; inflammation; type diabetes; tumor necrosis ... See more keywords
Effects of ambient particulate matter on a reconstructed human corneal epithelium model
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DOI: 10.1038/s41598-021-82971-1
Abstract: We evaluated the effects of ambient particulate matter (PM) on the corneal epithelium using a reconstructed human corneal epithelium (HCE) model. We collected two PM size fractions [aerodynamic diameter smaller than 2.4 µm: PM0.3–2.4 and… read more here.
Keywords: corneal; viability; corneal epithelium; effects ambient ... See more keywords
Morphological and immunohistochemical characteristics of the equine corneal epithelium
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary Ophthalmology"
DOI: 10.1111/vop.12651
Abstract: Abstract Objective The morphology of the corneal epithelium in two age groups of horses is described. Distribution patterns of proliferation‐, differentiation‐, stem cell‐associated markers and cell junction proteins were assessed. Methods Corneal samples from 12… read more here.
Keywords: equine corneal; epithelium; corneal epithelium; stem cell ... See more keywords
The Effect of para-Aminobenzoic Acid on Apoptosis Processes in the Adult Rat Conjunctiva and Corneal Epithelium in vivo after Hypobaric Hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Biology Bulletin"
DOI: 10.1134/s1062359018020061
Abstract: The initial stages of apoptotic damage to the conjunctiva and corneal epithelium, in the renewing cell populations of the eye has been studied in adult rats exposed to acute hypobaric hypoxia in vivo, and the… read more here.
Keywords: effect para; hypobaric hypoxia; corneal epithelium; effect ... See more keywords
Post-Ortho-K Corneal Epithelium Changes in Myopic Eyes
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/3361172
Abstract: The study is aimed at evaluating corneal epithelial thickness changes associated with overnight orthokeratology (ortho-K). In this retrospective study, epithelial thickness was measured using optical coherence tomography (OCT) before and after 1 day, 1 week,… read more here.
Keywords: corneal epithelium; epithelial thickness; thickness; temporal inferior ... See more keywords
Thickness profiles of the corneal epithelium along the steep and flat meridians of astigmatic corneas after orthokeratology
Sign Up to like & getrecommendations! Published in 2020 at "BMC Ophthalmology"
DOI: 10.1186/s12886-020-01477-y
Abstract: Background The aim of this study was to investigate the changes in corneal epithelial thickness along the principle meridians of astigmatic corneas after six months of overnight spherical myopic orthokeratology (OK) lens wear. Methods This… read more here.
Keywords: corneal toricity; corneal epithelium; thickness profiles; profiles corneal ... See more keywords
Corneal epithelium in keratoconus underexpresses active NRF2 and a subset of oxidative stress-related genes
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DOI: 10.1371/journal.pone.0273807
Abstract: Keratoconus (KC) is a multifactorial progressive ectatic disorder characterized by local thinning of the cornea, leading to decreased visual acuity due to irregular astigmatism and opacities. Despite the evolution of advanced imaging methods, the exact… read more here.
Keywords: corneal epithelium; stress; epithelium keratoconus; oxidative stress ... See more keywords
Comparison of cytotoxicity of fluoroquinolone antimicrobial eye drops and its effect on their bioavailability
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DOI: 10.17816/ov10177-86
Abstract: In addition to the breadth of activity of antibacterial medications as well as to their pharmacokinetic and pharmacodynamic properties, their safety and bioavailability represent an important aspect. Currently, there is no consensus on fluoroquinolone toxicity.… read more here.
Keywords: effect corneal; bioavailability; corneal epithelium; eye drops ... See more keywords