Intrastromal bevacizumab in the management of corneal neovascularization: a retrospective review
Sign Up to like & getrecommendations! Published in 2019 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-019-04519-4
Abstract: Purpose To evaluate the long-term safety and efficacy of intrastromal bevacizumab for treatment of deep corneal neovascularization in candidates for high-risk cornea grafting. Methods A single-center retrospective study involving 14 eyes of 14 patients with… read more here.
Keywords: corneal; intrastromal bevacizumab; bevacizumab management; corneal neovascularization ... See more keywords
Activation of Toll‐like receptor 3 promotes pathological corneal neovascularization by enhancement of SDF‐1‐mediated endothelial progenitor cell recruitment
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Eye Research"
DOI: 10.1016/j.exer.2018.10.005
Abstract: ABSTRACT Toll‐like receptors (TLRs) play an important role in inflammatory and immunological responses, which are intimately related to neovascularization. However, the precise mode of action of TLR3 in neovascularization still remains ambiguous. In this study,… read more here.
Keywords: toll like; pathological corneal; tlr3; corneal neovascularization ... See more keywords
Development of a naringenin microemulsion as a prospective ophthalmic delivery system for the treatment of corneal neovascularization: in vitro and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2021.2021323
Abstract: Abstract Naringenin, a flavonoid, possesses antiangiogenic potential and inhibits corneal neovascularization (CNV); however, its therapeutic use is restricted due to poor solubility and limited bioavailability. In this study, we developed a naringenin microemulsion (NAR-ME) for… read more here.
Keywords: corneal neovascularization; naringenin microemulsion; study; cnv ... See more keywords
Preparation and in vitro and in vivo evaluation of an isoliquiritigenin-loaded ophthalmic nanoemulsion for the treatment of corneal neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2096714
Abstract: Abstract Isoliquiritigenin (ISL), as a natural flavonoid, has been proven to have therapeutic potential for corneal neovascularization (CNV) treatment; however, its therapeutic use is restricted due to its poor aqueous solubility and limited bioavailability. To… read more here.
Keywords: corneal neovascularization; isl; treatment; isoliquiritigenin ... See more keywords
Corneal neovascularization inhibition and wound healing impregnability of conbercept on rabbit cornea after penetrating keratoplasty.
Sign Up to like & getrecommendations! Published in 2022 at "Cutaneous and ocular toxicology"
DOI: 10.1080/15569527.2022.2050745
Abstract: PURPOSE The inhibitory effect of conbercept on corneal neovascularization (CNV) after penetrating keratoplasty (PKP) and its effect on postoperative wound healing and corneal strength recovery was investigated. METHODS New Zealand white rabbits were randomly divided… read more here.
Keywords: wound healing; corneal neovascularization; conbercept; corneal ... See more keywords
Pharmacological Inhibition of Glutaminase 1 Attenuates Alkali-Induced Corneal Neovascularization by Modulating Macrophages
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1106313
Abstract: Corneal neovascularization (CoNV) in response to chemical burns is a leading cause of vision impairment. Although glutamine metabolism plays a crucial role in macrophage polarization, its regulatory effect on macrophages involved in chemical burn-induced corneal… read more here.
Keywords: inhibition; alkali induced; corneal neovascularization; conv ... See more keywords
An Update on Novel Ocular Nanosystems with Possible Benefits in the Treatment of Corneal Neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s375570
Abstract: Abstract Corneal neovascularization (CNV) is an ocular pathological change that results from an imbalance between angiogenic factors and antiangiogenic factors as a result of various ocular insults, including infection, inflammation, hypoxia, trauma, corneal degeneration, and… read more here.
Keywords: cnv; ocular nanosystems; corneal neovascularization; corneal ... See more keywords
Clinical and Histopathological Study of the Effect of Adipose-Derived Mesenchymal Stem Cells on Corneal Neovascularization following Alkali Burn in a Rabbit Model.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of Razi Institute"
DOI: 10.22092/ari.2022.357998.2136
Abstract: The cornea, the transparent part of the eye, performs a significant function in eyesight by refracting the light to focus a visual image. Since the cornea is indispensable for vision, corneal inflammation may induce visual… read more here.
Keywords: derived mesenchymal; corneal neovascularization; adipose derived; mesenchymal stem ... See more keywords
Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00111
Abstract: Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface. Fibroblast growth factor (FGF) family members play an important role in angiogenesis to induce corneal… read more here.
Keywords: growth factor; neovascularization; role; corneal neovascularization ... See more keywords
Salubrinal Ameliorates Inflammation and Neovascularization via the Caspase 3/Enos Signaling in an Alkaline-Induced Rat Corneal Neovascularization Model
Sign Up to like & getrecommendations! Published in 2023 at "Medicina"
DOI: 10.3390/medicina59020323
Abstract: Background and Objectives: Ocular alkaline burn is a clinical emergency that can cause permanent vision loss due to limbal stem cell deficiency and corneal neovascularization (CNV). Although the basic pathogenetic mechanisms are considered to be… read more here.
Keywords: stress; cnv; corneal neovascularization; corneal ... See more keywords
Topical application of TAK1 inhibitor encapsulated by gelatin particle alleviates corneal neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.65098
Abstract: Rationale: Corneal neovascularization (CoNV) is a severe complication of various types of corneal diseases, that leads to permanent visual impairment. Current treatments for CoNV, such as steroids or anti-vascular endothelial growth factor agents, are argued… read more here.
Keywords: topical application; oxozeaenol; inhibitor; corneal neovascularization ... See more keywords