Corneal nerve loss predicts dementia in patients with mild cognitive impairment
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51747
Abstract: This study compared the utility of corneal nerve measures with brain volumetry for predicting progression to dementia in individuals with mild cognitive impairment (MCI). read more here.
Keywords: mild cognitive; cognitive impairment; corneal nerve;
A comparison of the effects of different cap thicknesses on corneal nerve destruction after small incision lenticule extraction
Sign Up to like & getrecommendations! Published in 2020 at "International Ophthalmology"
DOI: 10.1007/s10792-020-01362-z
Abstract: Objective To evaluate the features of corneal nerve destruction after small incision lenticule extraction (SMILE) with different cap thicknesses (100 and 120 μm). Methods Nine consecutive patients (18 eyes) received SMILE with a 120-μm cap thickness… read more here.
Keywords: destruction small; nerve destruction; small incision; incision lenticule ... See more keywords
Computational methods for automated analysis of corneal nerve images: Lessons learned from retinal fundus image analysis
Sign Up to like & getrecommendations! Published in 2020 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2020.103666
Abstract: Corneal and retinal imaging provide a descriptive view of the nerve and vessel structure present inside the human eye, in a non-invasive manner. This helps in ocular, or other, disease identification and diagnosis. However, analyzing… read more here.
Keywords: corneal nerve; image analysis; analysis; corneal ... See more keywords
The effect of nerve growth factor on corneal nerve regeneration and dry eye after LASIK.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108428
Abstract: Dry eye is the most common complication after refractive surgery, especially after laser in situ keratomileusis (LASIK), in which nerves may be cut when making the corneal flap. Nerve growth factor (NGF) has been demonstrated… read more here.
Keywords: nerve; corneal nerve; eye; nerve regeneration ... See more keywords
Corneal nerve pathway function in individuals with dry eye symptoms.
Sign Up to like & getrecommendations! Published in 2020 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2020.07.061
Abstract: This prospective study characterized corneal nerve pathway function in individuals with dry eye symptoms. In total, 34% of individuals had a corneal sensitivity outside the 10-90% range or persistent pain after placement of topical anesthesia. read more here.
Keywords: individuals dry; nerve pathway; function individuals; pathway function ... See more keywords
The two-faced effects of nerves and neuropeptides in corneal diseases
Sign Up to like & getrecommendations! Published in 2021 at "Progress in retinal and eye research"
DOI: 10.1016/j.preteyeres.2021.100974
Abstract: Corneal nerves are instrumental to maintain cornea integrity through regulation of key physiological functions such as tear secretion, blink reflex, and neuropeptide turnover. Corneal nerve injury/stimulation can follow many insults including mechanical/chemical trauma, infections and… read more here.
Keywords: neurogenic inflammation; two faced; corneal; faced effects ... See more keywords
The Examination on Corneal Nerve in Diabetic WBN/Kob Rat is Useful for Detecting Peripheral Sensory Neuropathy
Sign Up to like & getrecommendations! Published in 2019 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927619006470
Abstract: Corneal confocal microscopy (CCM) has been used to evaluate small nerve fibers in the cornea [1]. CCM studies also have revealed that the density of nerve fibers in the subbasal nerve plexus (SBNP) correlates with… read more here.
Keywords: nerve; microscopy; sensory; corneal nerve ... See more keywords
Comparative quantitative assessment of the human corneal sub-basal nerve plexus by in vivo confocal microscopy and histological staining
Sign Up to like & getrecommendations! Published in 2017 at "Eye"
DOI: 10.1038/eye.2016.220
Abstract: PurposeThis study was designed to compare and contrast quantitative data of the human corneal sub-basal nerve plexus (SBP) evaluated by two different methods: in vivo confocal microscopy (IVCM), and immunohistochemical staining of ex vivo donor… read more here.
Keywords: nerve; corneal sub; microscopy; human corneal ... See more keywords
Corneal nerve loss as a surrogate marker for poor pial collaterals in patients with acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-99131-0
Abstract: In patients with acute ischemic stroke, pial collaterals play a key role in limiting neurological disability by maintaining blood flow to ischemic penumbra. We hypothesized that patient with poor pial collaterals will have greater corneal… read more here.
Keywords: patients acute; corneal nerve; ischemic stroke; pial collaterals ... See more keywords
Abnormal corneal nerve morphology and brain volume in patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-05609-w
Abstract: Neurodevelopmental and neurodegenerative pathology occur in Schizophrenia. This study compared the utility of corneal confocal microscopy (CCM), an ophthalmic imaging technique with MRI brain volumetry in quantifying neuronal pathology and its relationship to cognitive dysfunction… read more here.
Keywords: corneal; corneal nerve; pathology; volume ... See more keywords
Corneal confocal microscopy meets continuous glucose monitoring: a tale of two technologies
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002254
Abstract: Zhao et al [1] from Shanghai, China, have undertaken a detailed clinical study in a cohort of 206 asymptomatic patients with type 2 diabetes utilizing advanced in vivo nerve imaging with corneal confocal microscopy (CCM-Heidelberg… read more here.
Keywords: corneal confocal; glucose monitoring; continuous glucose; microscopy ... See more keywords