Corneal Wound Associated With Orthokeratology Lenses.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.3044
Abstract: This case report describes a diagnosis of corneal epithelial defect after a patient presentation of eye pain and tearing with orthokeratology lens wear. read more here.
Keywords: ophthalmology; corneal wound; orthokeratology lenses; associated orthokeratology ... See more keywords
Wireless‐Powered Electrical Bandage Contact Lens for Facilitating Corneal Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202202506
Abstract: Corneal injury can lead to severe vision impairment or even blindness. Although numerous methods are developed to accelerate corneal wound healing, most of them are passive treatments that rarely participate in controlling endogenous cell behaviors… read more here.
Keywords: wound healing; corneal wound; contact lens; corneal ... See more keywords
Corneal wound healing.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108089
Abstract: The corneal wound healing response is typically initiated by injuries to the epithelium and/or endothelium that may also involve the stroma. However, it can also be triggered by immune or infectious processes that enter the… read more here.
Keywords: wound healing; fibrosis; corneal wound; apoptosis ... See more keywords
Topical Administration of Spironolactone-Loaded Nanomicelles Prevents Glucocorticoid-Induced Delayed Corneal Wound Healing in Rabbits.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b01028
Abstract: The objective was to investigate whether mineralocorticoid receptor antagonism using a novel topical micellar formulation of spironolactone could prevent glucocorticoid-induced delayed corneal wound healing in New Zealand white rabbits. Spironolactone micelles (0.1%, w/v) with a… read more here.
Keywords: wound healing; glucocorticoid induced; induced delayed; spironolactone ... See more keywords
Gelatin hydrogel/contact lens composites as rutin delivery systems for promoting corneal wound healing
Sign Up to like & getrecommendations! Published in 2021 at "Drug Delivery"
DOI: 10.1080/10717544.2021.1979126
Abstract: Abstract Corneal wound healing is a highly regulated biological process that is of importance for reducing the risk of blinding corneal infections and inflammations. Traditional eye drop was the main approach for promoting corneal wound… read more here.
Keywords: wound healing; gelatin hydrogel; promoting corneal; hydrogel contact ... See more keywords
Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in Corneal Wound Healing Deficiency Through Inhibition of Canonical Wnt Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db21-0740
Abstract: It was reported previously that circulation levels of kallistatin, an endogenous Wnt signaling inhibitor, are increased in patients with diabetes. The current study was conducted to determine the role of kallistatin in delayed wound healing… read more here.
Keywords: wound healing; corneal wound; kallistatin; wnt ... See more keywords
Therapeutic Potential of Peucedanum japonicum Thunb. and Its Active Components in a Delayed Corneal Wound Healing Model Following Blue Light Irradiation-Induced Oxidative Stress
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12061171
Abstract: Blue light is reported to be harmful to eyes by inducing reactive oxygen species (ROS). Herein, the roles of Peucedanum japonicum Thunb. leaf extract (PJE) in corneal wound healing under blue light irradiation are investigated.… read more here.
Keywords: wound healing; japonicum thunb; blue light; corneal wound ... See more keywords
Quantitative Proteomics Reveals Molecular Network Driving Stromal Cell Differentiation: Implications for Corneal Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052572
Abstract: The differentiation of keratocytes to fibroblasts and myofibroblasts is an essential requisite during corneal wound closure. The aim of this study is to uncover factors involved in differentiation-dependent alteration in the protein profile of human… read more here.
Keywords: cell; wound healing; corneal wound; corneal ... See more keywords
Shhedding New Light on the Role of Hedgehog Signaling in Corneal Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073630
Abstract: The cornea, an anterior ocular tissue that notably serves to protect the eye from external insults and refract light, requires constant epithelium renewal and efficient healing following injury to maintain ocular homeostasis. Although several key… read more here.
Keywords: hedgehog signaling; wound healing; role; corneal wound ... See more keywords
Transcriptomic Profiling of Human Limbus-Derived Stromal/Mesenchymal Stem Cells—Novel Mechanistic Insights into the Pathways Involved in Corneal Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158226
Abstract: Limbus-derived stromal/mesenchymal stem cells (LMSCs) are vital for corneal homeostasis and wound healing. However, despite multiple pre-clinical and clinical studies reporting the potency of LMSCs in avoiding inflammation and scarring during corneal wound healing, the… read more here.
Keywords: derived stromal; wound healing; corneal wound; stem ... See more keywords