Preferential arrangement of lipids in the long-periodicity phase of a stratum corneum matrix model[S]
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DOI: 10.1194/jlr.m087106
Abstract: The lipid matrix of the stratum corneum, the outermost skin layer, consists primarily of ceramides, cholesterol, and FFAs. These lipids form a trilayer long-periodicity phase (LPP) that is unique to this barrier. Knowledge about the… read more here.
Keywords: stratum corneum; periodicity phase; matrix; corneum ... See more keywords
Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency[S]
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DOI: 10.1194/jlr.p087536
Abstract: Neu-Laxova syndrome (NLS) is a very rare autosomal recessive congenital disorder characterized by disturbed development of the central nervous system and the skin and caused by mutations in any of the three genes involved in… read more here.
Keywords: stratum corneum; phosphoglycerate dehydrogenase; neu laxova; laxova syndrome ... See more keywords
The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions
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DOI: 10.3390/ijms23137486
Abstract: We evaluated the presence of tight junction (TJ) remnants in the stratum corneum (SC) of in vitro reconstructed human epidermis and human skin explants subjected or not to an aggressive topical treatment with beta-lipohydroxy salicylic… read more here.
Keywords: fate epidermal; stratum corneum; tight junctions; epidermal tight ... See more keywords