Aqueous extracts of Corni Fructus protect C2C12 myoblasts from DNA damage and apoptosis caused by oxidative stress.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-022-07332-1
Abstract: BACKGROUND Although the various pharmacological effects of Corni Fructus are highly correlated with its antioxidant activity, the blocking effect against oxidative stress in muscle cells is not clear. The purpose of this study was to… read more here.
Keywords: damage; stress; apoptosis; corni fructus ... See more keywords
Undescribed morroniside-like secoiridoid diglycosides with α-glucosidase inhibitory activity from Corni Fructus.
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2019.112232
Abstract: Corni Fructus, also known as the fruit of Cornus officinalis Sieb. et Zucc., has long been used as a traditional Chinese medicine and is widely consumed as a nutritional food in the form of function… read more here.
Keywords: fructus; corni fructus; inhibitory activity; glucosidase inhibitory ... See more keywords
Protective Effects of Iridoid Glycoside from Corni Fructus on Type 2 Diabetes with Nonalcoholic Fatty Liver in Mice
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/3642463
Abstract: Type 2 diabetes mellitus (T2DM) is a common chronic metabolic disease. Accumulating evidence has demonstrated that nonalcoholic fatty liver disease (NAFLD) shares common typical features with T2DM, and they affect each other extensively. Thus, NAFLD… read more here.
Keywords: fatty liver; effects iridoid; type diabetes; t2dm nafld ... See more keywords
Corni Fructus Alleviates UUO-Induced Renal Fibrosis via TGF-β/Smad Signaling
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DOI: 10.1155/2022/5780964
Abstract: Renal fibrosis is a type of chronic kidney disease (CKD) induced by infiltration of inflammatory cells, myofibroblast accumulation, and ECM production in the kidney. From a long time ago, Corni Fructus (CF) is known to… read more here.
Keywords: kidney; renal fibrosis; tgf smad; corni fructus ... See more keywords
Corni Fructus: a review of chemical constituents and pharmacological activities
Sign Up to like & getrecommendations! Published in 2018 at "Chinese Medicine"
DOI: 10.1186/s13020-018-0191-z
Abstract: Cornus officinalis Sieb. et Zucc. is part of the genus Cornus of the family Cornaceae. Ripening and dry fruits (Corni Fructus) are recognized as an essential herb medicine in the traditional Chinese medicine (TCM) and… read more here.
Keywords: medicine; pharmacological activities; review chemical; fructus review ... See more keywords
A systematic review on anti-diabetic action of 7-O-galloyl-D-sedoheptulose, a polyphenol from Corni Fructus, in type 2 diabetic mice with hepatic and pancreatic damage.
Sign Up to like & getrecommendations! Published in 2023 at "Drug discoveries & therapeutics"
DOI: 10.5582/ddt.2022.01097
Abstract: Traditional medicines are recently being focused on to treat diabetes and its complications because of their lack of toxic and/or side effects. This report describes the effects of 7-O-galloyl-D-sedoheptulose (GS), a polyphenolic compound isolated from… read more here.
Keywords: type diabetic; corni fructus; diabetic mice; galloyl sedoheptulose ... See more keywords