Association of coronary microvascular dysfunction and cardiac bridge integrator 1, a cardiomyocyte dysfunction biomarker.
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DOI: 10.1002/clc.23726
Abstract: BACKGROUND Coronary microvascular dysfunction (CMD) is associated with heart failure with preserved ejection fraction (HFpEF); however, pathophysiology is not well described. HYPOTHESIS We hypothesized that CMD in women with suspected ischemia with no obstructive coronary… read more here.
Keywords: microvascular dysfunction; cardiomyocyte; dysfunction; cardiac bridge ... See more keywords
Coronary microvascular dysfunction in Takotsubo syndrome and associations with left ventricular function.
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DOI: 10.1002/ehf2.14394
Abstract: AIMS Coronary microvascular dysfunction (CMD) has been proposed as an important pathophysiological mechanism in Takotsubo syndrome (TTS). Our aims were (i) to evaluate and compare levels of CMD in patients with TTS and patients with… read more here.
Keywords: ventricular function; microvascular dysfunction; tts; coronary microvascular ... See more keywords
Endothelium‐dependent and independent coronary microvascular dysfunction in patients with heart failure with preserved ejection fraction
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.1671
Abstract: Coronary microvascular inflammation is hypothesized to play a fundamental role in the pathophysiology of heart failure with preserved ejection fraction (HFpEF). No study has directly evaluated both endothelium‐dependent and independent coronary microvascular function in HFpEF. read more here.
Keywords: preserved ejection; failure preserved; coronary microvascular; heart failure ... See more keywords
Coronary microvascular dysfunction in heart failure with preserved ejection fraction – adding new pieces to the jigsaw puzzle
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DOI: 10.1002/ejhf.1720
Abstract: 1Charité Universitätsmedizin Berlin, BCRT Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany; 2German Center for Cardiovascular Research (DZHK), partner site Berlin, Berlin, Germany; 3Vita Salute University and San Raffaele Hospital, Milan, Italy; 4CNR… read more here.
Keywords: heart; berlin germany; microvascular dysfunction; heart failure ... See more keywords
MRI assessment of coronary microvascular endothelial nitric oxide synthase function using myocardial T1 mapping
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DOI: 10.1002/mrm.26870
Abstract: Endothelial nitric oxide synthase (eNOS) plays a central role in regulating vascular tone, blood flow, and microvascular permeability. Endothelial dysfunction, including eNOS dysfunction, is an early biomarker of vascular disease. This study aimed to show… read more here.
Keywords: endothelial nitric; oxide synthase; nitric oxide; coronary microvascular ... See more keywords
Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance.
Sign Up to like & getrecommendations! Published in 2022 at "Angiogenesis"
DOI: 10.1007/s10456-022-09835-8
Abstract: Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes, and can accelerate diabetes-related microvascular and macrovascular complications by promoting vasoconstrictive, pro-inflammatory and pro-thrombotic responses. Perturbed mitochondrial function induces oxidative stress, disrupts… read more here.
Keywords: coronary microvascular; mitochondrial quality; microvascular endothelial; endothelial dysfunction ... See more keywords
Coronary microvascular dysfunction, left ventricular remodeling, and clinical outcomes in aortic stenosis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Nuclear Cardiology"
DOI: 10.1007/s12350-019-01706-y
Abstract: BackgroundWe investigated role of coronary microvascular disease (CMD) in maladaptive LV remodeling and prognosis in patients with aortic sclerosis or stenosis and no overt CAD.MethodsThis was a retrospective cohort study of patients with aortic sclerosis… read more here.
Keywords: gls; microvascular dysfunction; mfr; stenosis ... See more keywords
Questionnaire survey on cardiologists’ view and management of coronary microvascular disease in clinical practice
Sign Up to like & getrecommendations! Published in 2019 at "Netherlands Heart Journal"
DOI: 10.1007/s12471-019-1274-x
Abstract: ObjectiveWe aimed to assess the opinion of Dutch cardiologists on coronary microvascular disease (CMD) and its management in clinical practice, and to assess the need for a CMD guideline among Dutch cardiologists.MethodsWe developed an online questionnaire… read more here.
Keywords: cardiology; cmd; disease; questionnaire ... See more keywords
Platelet reactivity and coronary microvascular impairment after percutaneous revascularization in stable patients receiving clopidogrel or prasugrel.
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DOI: 10.1016/j.atherosclerosis.2018.08.044
Abstract: BACKGROUND AND AIMS Increased platelet reactivity (PR) associated with variable degree of coronary microvascular impairment has been reported in patients on clopidogrel after elective percutaneous coronary intervention (PCI). Prasugrel provides more potent platelet inhibition than… read more here.
Keywords: prasugrel; clopidogrel; microvascular impairment; pci ... See more keywords
Elevated renalase levels in patients with acute coronary microvascular dysfunction - A possible biomarker for ischemia.
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DOI: 10.1016/j.ijcard.2018.12.061
Abstract: AIMS We explored the relationship between inflammation, renalase an anti-inflammatory protein, and acute chest pain with coronary microvascular dysfunction (CMD). METHODS AND RESULTS We used cardiac Rb-82 PET/CT imaging to diagnose coronary artery disease (CAD/CALC)… read more here.
Keywords: cmd; microvascular dysfunction; elevated renalase; renalase ... See more keywords
Coronary Microvascular Dysfunction Identifies Patients at High Risk of Adverse Events Across Cardiometabolic Diseases.
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DOI: 10.1016/j.jacc.2017.09.1104
Abstract: Patients with metabolic syndrome (MetS) and diabetes mellitus (DM) are at increased risk for coronary artery disease (CAD) and heart failure [(1)][1]. Impaired coronary flow reserve (CFR), the ratio of stress to rest myocardial blood… read more here.
Keywords: risk; dysfunction identifies; microvascular dysfunction; identifies patients ... See more keywords