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Published in 2021 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.1c00319
Abstract: A series of nondeuterated and deuterated dipeptidyl aldehyde and masked aldehyde inhibitors that incorporate in their structure a conformationally constrained cyclohexane moiety was synthesized and found to potently inhibit severe acute respiratory syndrome coronavirus-2 3CL…
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Keywords:
respiratory syndrome;
3cl protease;
coronavirus 3cl;
syndrome coronavirus ... See more keywords
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Published in 2021 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201022666210604150041
Abstract: BACKGROUND There has been tremendous pressure on healthcare facilities globally due to the recent emergence of novel coronavirus infections known as COVID-19 and its rapid spread across the continents. The lack of effective therapeutics for…
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Keywords:
coronavirus 3cl;
cov 3clpro;
3cl like;
like protease ... See more keywords