MK212, a 5-hydroxytryptamine 2C receptor agonist, reverses prepulse inhibition deficits in the medial prefrontal cortex and ventral hippocampus
Sign Up to like & getrecommendations! Published in 2022 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2021.110441
Abstract: Prepulse inhibition (PPI) is disrupted in many neuropsychiatric diseases. Molecules such as 5-HT2C receptor agonists alleviate PPI deficits in rodents; however, the precise mechanisms and critical regions of the brain responsible for the reversal effect… read more here.
Keywords: ppi deficits; medial prefrontal; ht2c receptor; receptor ... See more keywords
Defining the interconnectivity of the medial prefrontal cortex and ventral midbrain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.971349
Abstract: Dysfunction in dopamine (DA) signaling contributes to neurological disorders ranging from drug addiction and schizophrenia to depression and Parkinson’s Disease. How might impairment of one neurotransmitter come to effect these seemingly disparate diseases? One potential… read more here.
Keywords: cortex ventral; medial prefrontal; defining interconnectivity; interconnectivity medial ... See more keywords