Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Immunology"
DOI: 10.1002/eji.202350774
Abstract: The structure and dynamics of F‐actin networks in the cortical area of B cells control the signal efficiency of B‐cell antigen receptors (BCRs). Although antigen‐induced signaling has been studied extensively, the role of cortical F‐actin… read more here.
Keywords: antigen; cell; antigen receptors; cortical actin ... See more keywords
Cortical Actin Depolymerisation in 3D Cell Culture Enhances Extracellular Vesicle Secretion and Therapeutic Effects
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70109
Abstract: ABSTRACT Three‐dimensional (3D) culture systems have been shown to enhance cellular secretion of small extracellular vesicles (sEVs) compared to two‐dimensional (2D) culture. However, the molecular mechanisms driving sEV secretion and influencing their potential for disease… read more here.
Keywords: actin depolymerisation; culture; cell; secretion ... See more keywords
Real-time imaging of individual virion-triggered cortical actin dynamics for human immunodeficiency virus entry into resting CD4 T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c9nr07359k
Abstract: Real-time imaging of single virus particles allows the visualization of subtle dynamic events of virus-host interaction. During the human immunodeficiency virus (HIV) infection of resting CD4 T lymphocytes, overcoming cortical actin restriction is an essential… read more here.
Keywords: real time; actin; time imaging; entry ... See more keywords
The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.1101/2022.06.15.496320
Abstract: Defective nutrient storage and adipocyte enlargement (hypertrophy) are emerging features of metabolic syndrome and type 2 diabetes. Within adipose tissues, how the cytoskeletal network contributes to adipose cell size, nutrient uptake, fat storage, and signaling… read more here.
Keywords: size; cortical actin; cell; actin network ... See more keywords
Plekhh1, a partner of myosin 1 and an effector of EphB2 controls the cortical actin network for cell repulsion.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cell science"
DOI: 10.1242/jcs.258802
Abstract: EphB2/ephrinB signalling that plays a major role in cell segregation during embryonic development and tissue homeostasis, induces an important reorganization of the cortical actin network. We have previously reported that myosin 1b contributes to the… read more here.
Keywords: cortical actin; actin network; myosin; ephb2 ... See more keywords
Fos regulates macrophage infiltration against surrounding tissue resistance by a cortical actin-based mechanism in Drosophila
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Biology"
DOI: 10.1371/journal.pbio.3001494
Abstract: The infiltration of immune cells into tissues underlies the establishment of tissue-resident macrophages and responses to infections and tumors. Yet the mechanisms immune cells utilize to negotiate tissue barriers in living organisms are not well… read more here.
Keywords: infiltration; drosophila; actin; cortical actin ... See more keywords
Cortical actin nodes: Their dynamics and recruitment of podosomal proteins as revealed by super-resolution and single-molecule microscopy
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0188778
Abstract: Electron tomography of the plasma membrane (PM) identified several layers of cortical actin meshwork running parallel to the PM cytoplasmic surface throughout the PM. Here, cortical actin structures and dynamics were examined in living cells,… read more here.
Keywords: cortical actin; actin clusters; super resolution; microscopy ... See more keywords
Embedding of HIV Egress within Cortical F-Actin
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11010056
Abstract: F-Actin remodeling is important for the spread of HIV via cell–cell contacts; however, the mechanisms by which HIV corrupts the actin cytoskeleton are poorly understood. Through live cell imaging and focused ion beam scanning electron… read more here.
Keywords: cortical actin; cell; hiv egress; hiv ... See more keywords