Focal cortical atrophy following transient meningeal enhancement in a progressive multiple sclerosis
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DOI: 10.1007/s10072-020-04764-0
Abstract: Recent studies identified chronic leptomeningeal enhancement (LME) in late-acquired FLAIR sequences in secondary progressive (SP) multiple sclerosis (MS). These LMEs correlate with focal cortical inflammation and demyelination observed by pathology, which are supposed to drive… read more here.
Keywords: focal cortical; progressive multiple; multiple sclerosis; cortical atrophy ... See more keywords
Executive dysfunction contributes to verbal encoding and retrieval deficits in posterior cortical atrophy
Sign Up to like & getrecommendations! Published in 2018 at "Cortex"
DOI: 10.1016/j.cortex.2018.04.010
Abstract: Posterior Cortical Atrophy (PCA) is a neurodegenerative syndrome that typically presents with predominant visual and spatial impairments. The early diagnostic criteria specify a relative sparing of functioning in other cognitive domains, including executive functions, language,… read more here.
Keywords: memory; posterior cortical; executive; pca ... See more keywords
Impaired visual search in posterior cortical atrophy vs. typical Alzheimer's disease
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2021.117574
Abstract: BACKGROUND Posterior cortical atrophy (PCA) is a neurocognitive disorder characterized by difficulty localizing in space. Recognizing PCA is important because it is usually missed early in its course and may result from a number of… read more here.
Keywords: impaired visual; search; posterior cortical; alzheimer disease ... See more keywords
Permutation-based inference for spatially localized signals in longitudinal MRI data
Sign Up to like & getrecommendations! Published in 2021 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2021.118312
Abstract: Alzheimer's disease is a neurodegenerative disease in which the degree of cortical atrophy in specific structures of the brain serves as a useful imaging biomarker. Recent approaches using linear mixed effects (LME) models in longitudinal… read more here.
Keywords: inference spatially; cortical atrophy; based inference; permutation based ... See more keywords
Posterior cortical atrophy: clinical, neuroimaging, and neuropathological features
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2023.2190885
Abstract: ABSTRACT Introduction Posterior Cortical Atrophy (PCA) is a neurodegenerative disorder characterized by impairment of higher-order visual processing in the setting of progressive atrophy of the parietal and occipital lobes. The underlying pathology is variable but… read more here.
Keywords: posterior cortical; cortical atrophy; alzheimer disease; pathology ... See more keywords
Impairments of auditory scene analysis in posterior cortical atrophy
Sign Up to like & getrecommendations! Published in 2020 at "Brain"
DOI: 10.1093/brain/awaa221
Abstract: Abstract Although posterior cortical atrophy is often regarded as the canonical ‘visual dementia’, auditory symptoms may also be salient in this disorder. Patients often report particular difficulty hearing in busy environments; however, the core cognitive… read more here.
Keywords: posterior cortical; cortical atrophy; scene analysis; auditory scene ... See more keywords
Systemic exertion intolerance disease associated to neuroendocrine dysfunction and cortical atrophy: a case report.
Sign Up to like & getrecommendations! Published in 2022 at "Family practice"
DOI: 10.1093/fampra/cmac060
Abstract: BACKGROUND Scarce evidence about the organic and functional abnormalities of systemic exertion intolerance disease (SEID) is found in literature and the pathophysiology is still unclear. METHODS Following the CARE Guidelines, this case report describes a… read more here.
Keywords: intolerance disease; cortical atrophy; case report; exertion intolerance ... See more keywords
Posterior cortical atrophy: Primary occipital variant
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15327
Abstract: Posterior cortical atrophy (PCA) is one of the atypical Alzheimer's disease variants, characterized by predominant visuospatial and visuoperceptual deficits, with established dorsal and ventral subtypes. A third primary occipital (caudal) variant has been suggested. We… read more here.
Keywords: posterior cortical; cortical atrophy; variant; primary occipital ... See more keywords
Clinical and metabolic imaging features of late‐onset and early‐onset posterior cortical atrophy
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15520
Abstract: Late‐onset (LO) and early‐onset (EO) dementia show neurobiological and clinical differences. Clinical and 18fluoro‐deoxy‐glucose positron emission tomography (FDG‐PET) features of LO and EO posterior cortical atrophy (LO_PCA, EO_PCA), the visual variant of Alzheimer's disease (AD),… read more here.
Keywords: posterior cortical; cortical atrophy; onset early; early onset ... See more keywords
Related amyloid burden and cortical atrophy in individuals with subtle cognitive decline
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroimaging"
DOI: 10.1111/jon.13055
Abstract: Subtle cognitive decline represents a stage of cognitive deterioration in which pathological biomarkers may be present, including early cortical atrophy and amyloid deposition. Using individual items from the Montreal Cognitive Assessment and k‐modes cluster analysis,… read more here.
Keywords: subtle cognitive; cortical atrophy; amyloid burden; atrophy ... See more keywords
Patterns of longitudinal cortical atrophy over 3 years in empirically derived MCI subtypes
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DOI: 10.1212/wnl.0000000000009462
Abstract: Objective We previously identified 4 empirically derived mild cognitive impairment (MCI) subtypes via cluster analysis within the Alzheimer's Disease Neuroimaging Initiative (ADNI) and demonstrated high correspondence between patterns of cortical thinning at baseline and each… read more here.
Keywords: atrophy years; mci subtypes; atrophy; cortical atrophy ... See more keywords