Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09999-w
Abstract: Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are… read more here.
Keywords: dynein dynactin; numa lgn; cortical force; lgn ... See more keywords
Direct measurement of cortical force generation and polarization in a living parasite
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-07-0518
Abstract: A laser trap was used to measure the molecular-scale forces generated at the surface of living Toxoplasma gondii in order to test the dominant theory of how these parasites move and invade host cells. The… read more here.
Keywords: direct measurement; measurement cortical; cortical force; force generation ... See more keywords