Generation of cerebral cortical GABAergic interneurons from pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2020 at "STEM CELLS"
DOI: 10.1002/stem.3252
Abstract: The cerebral cortex functions by the complex interactions of intrinsic and extrinsic neuronal activities, glial actions, and the effects of humoral factors. The intrinsic neuronal influences are mediated by two major subclasses: excitatory glutamatergic neurons… read more here.
Keywords: cortical gabaergic; generation; pluripotent stem; gabaergic interneurons ... See more keywords
Ischemia deteriorates spike encoding at cortical GABAergic neurons and cerebellar Purkinje cells by increasing the intracellular Ca2+
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2017.03.005
Abstract: GABAergic neurons play a critical role in the central nervous system, such as well-organized behaviors. The ischemic cell death is presumably initiated by neuronal excitotoxicity resulted from the dysfunction of GABAergic neurons. It is not… read more here.
Keywords: cortical gabaergic; ischemia; intracellular ca2; spike encoding ... See more keywords
Abnormalities in Cortical GABAergic Interneurons of the Primary Motor Cortex Caused by Lis1 (Pafah1b1) Mutation Produce a Non-drastic Functional Phenotype
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.769853
Abstract: LIS1 (PAFAH1B1) plays a major role in the developing cerebral cortex, and haploinsufficient mutations cause human lissencephaly type 1. We have studied morphological and functional properties of the cerebral cortex of mutant mice harboring a… read more here.
Keywords: gabaergic interneurons; lis1 pafah1b1; cortical gabaergic; phenotype ... See more keywords