Cortical hyperexcitability evolves with disease progression in ALS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51039
Abstract: Cortical hyperexcitability has been established as an early feature of amyotrophic lateral sclerosis (ALS). The evolution of cortical hyperexcitability with ALS progression remains to be fully elucidated. This study aims to investigate changes in cortical… read more here.
Keywords: hyperexcitability; cortical hyperexcitability; hyperexcitability evolves; disease progression ... See more keywords
Stimulus-Driven Cortical Hyperexcitability in Individuals with Charles Bonnet Hallucinations
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.08.058
Abstract: Throughout the lifespan, the cerebral cortex adapts its structure and function in response to changing sensory input [1, 2]. Whilst such changes are typically adaptive, they can be maladaptive when they follow damage to the… read more here.
Keywords: hyperexcitability; cortical hyperexcitability; field; peripheral visual ... See more keywords
Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0053-1
Abstract: SummaryLysophosphatidic acid (LPA) is a synaptic phospholipid, which regulates cortical excitation/inhibition (E/I) balance and controls sensory information processing in mice and man. Altered synaptic LPA signaling was shown to be associated with psychiatric disorders. Here,… read more here.
Keywords: psychiatric disorders; inhibition; cortical hyperexcitability; atx inhibition ... See more keywords
Cortical hyperexcitability and plasticity in Alzheimer’s disease: developments in understanding and management
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2022.2170784
Abstract: ABSTRACT Introduction Transcranial magnetic stimulation (TMS) is a non-invasive neurophysiological tool that provides important insights into Alzheimer’s Disease (AD). A significant body of work utilizing TMS techniques has explored the pathophysiological relevance of cortical hyperexcitability… read more here.
Keywords: tms; hyperexcitability plasticity; alzheimer disease; plasticity ... See more keywords