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   Articles with "cortical layer" as a keyword



Cux2 expression regulated by Lhx2 in the upper layer neurons of the developing cortex.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.11.004

Abstract: The laminar structure, a unique feature of the mammalian cerebrum, is formed by a number of genes in a highly complex process. The pyramidal neurons that make up each layer of the cerebrum are functionally… read more here.

Keywords: expression regulated; layer neurons; cortical layer; expression ... See more keywords
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Neonatal Tbr1 Dosage Controls Cortical Layer 6 Connectivity

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recommendations! Published in 2018 at "Neuron"

DOI: 10.1016/j.neuron.2018.09.027

Abstract: An understanding of how heterozygous loss-of-function mutations in autism spectrum disorder (ASD) risk genes, such as TBR1, contribute to ASD remains elusive. Conditional Tbr1 deletion during late mouse gestation in cortical layer 6 neurons (Tbr1layer6… read more here.

Keywords: tbr1 dosage; cortical layer; layer; neonatal tbr1 ... See more keywords

Maternal usage of varying levels of dietary folate affects the postnatal development of cerebellar folia and cortical layer volumes

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recommendations! Published in 2024 at "Nutritional Neuroscience"

DOI: 10.1080/1028415x.2024.2312304

Abstract: ABSTRACT Objective The cerebellum has a long, protracted developmental period; therefore, it is more sensitive to intrauterine and postnatal insults like nutritional deficiencies. Folate is an essential nutrient in fetal and postnatal brain development, and… read more here.

Keywords: development; folate; cerebellar folia; cortical layer ... See more keywords

Upper cortical layer–driven network impairment in schizophrenia

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recommendations! Published in 2022 at "Science Advances"

DOI: 10.1126/sciadv.abn8367

Abstract: Schizophrenia is one of the most widespread and complex mental disorders. To characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing (snRNA-seq) of >220,000 neurons from the dorsolateral prefrontal cortex of patients with schizophrenia… read more here.

Keywords: upper cortical; cortical layer; layer; network impairment ... See more keywords