Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2019.5106
Abstract: Importance Neuropathology studies show a high prevalence of cortical microinfarcts (CMIs) in aging individuals, especially in patients with cerebrovascular disease and dementia. However, most, are invisible on T1- and T2-weighted magnetic resonance imaging (MRI), raising… read more here.
Keywords: cerebral small; cmi; small vessel; cortical microinfarcts ... See more keywords
Single Cortical Microinfarcts Lead to Widespread Microglia/Macrophage Migration Along the White Matter.
Sign Up to like & getrecommendations! Published in 2020 at "Cerebral cortex"
DOI: 10.1093/cercor/bhaa223
Abstract: Loss of cognitive function with aging is a complex and poorly understood process. Recently, clinical research has linked the occurrence of cortical microinfarcts to cognitive decline. Cortical microinfarcts form following the occlusion of penetrating vessels… read more here.
Keywords: microglia macrophage; microinfarcts lead; cortical microinfarcts; single cortical ... See more keywords
Association of cortical microinfarcts and cerebral small vessel pathology in the ageing brain
Sign Up to like & getrecommendations! Published in 2017 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12366
Abstract: Cortical microinfarcts (CMI) are frequently observed in the ageing brain independent of cognitive decline, but their aetiology is not fully elucidated. To examine the potential role of different vessel pathologies, including cerebral amyloid angiopathy (CAA),… read more here.
Keywords: vessel; pathology; ageing brain; cortical microinfarcts ... See more keywords
Aβ (Amyloid Beta) and Tau Tangle Pathology Modifies the Association Between Small Vessel Disease and Cortical Microinfarcts
Sign Up to like & getrecommendations! Published in 2021 at "Stroke"
DOI: 10.1161/strokeaha.120.031073
Abstract: Supplemental Digital Content is available in the text. Background and Purpose: There is increasing recognition of the importance of cortical microinfarcts to overall brain health, cognition, and Alzheimer dementia. Cerebral small vessel pathologies are associated… read more here.
Keywords: pathology; cortical microinfarcts; small vessel; tau tangle ... See more keywords