Epigenomic diversity of cortical projection neurons in the mouse brain
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03223-w
Abstract: Neuronal cell types are classically defined by their molecular properties, anatomy and functions. Although recent advances in single-cell genomics have led to high-resolution molecular characterization of cell type diversity in the brain1, neuronal cell types… read more here.
Keywords: cortico cortical; diversity; projection neurons; projection ... See more keywords
Transcription Factors Bcl11a and Bcl11b Are Required for the Production and Differentiation of Cortical Projection Neurons.
Sign Up to like & getrecommendations! Published in 2021 at "Cerebral cortex"
DOI: 10.1093/cercor/bhab437
Abstract: The generation and differentiation of cortical projection neurons are extensively regulated by interactive programs of transcriptional factors. Here, we report the cooperative functions of transcription factors Bcl11a and Bcl11b in regulating the development of cortical… read more here.
Keywords: projection neurons; differentiation cortical; bcl11a bcl11b; projection ... See more keywords
FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abh3568
Abstract: The mammalian neocortex is a highly organized six-layered structure with four major cortical neuron subtypes: corticothalamic projection neurons (CThPNs), subcerebral projection neurons (SCPNs), deep callosal projection neurons (CPNs), and superficial CPNs. Here, careful examination of… read more here.
Keywords: postmitotic cortical; projection; cortical projection; projection neurons ... See more keywords