Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16046-6
Abstract: Deep brain stimulation (DBS) of the subthalamic nucleus is a symptomatic treatment of Parkinson’s disease but benefits only to a minority of patients due to stringent eligibility criteria. To investigate new targets for less invasive therapies,… read more here.
Keywords: deep brain; stimulation; cortical somatostatin; brain stimulation ... See more keywords
Commentary: Activation of Cortical Somatostatin Interneurons Rescues Synapse Loss and Motor Deficits After Acute MPTP Infusion
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00544
Abstract: Guangdong Provincial Key Laboratory of Sports and Health Promotion, Scientific Research Center, Guangzhou Sport University, Guangzhou, China, Department of Rehabilitation, Shanghai Putuo People’s Hospital, Shanghai, China, 3 Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental… read more here.
Keywords: commentary activation; activation cortical; china; somatostatin interneurons ... See more keywords
Complementary networks of cortical somatostatin interneurons enforce layer specific control
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.43696
Abstract: The neocortex is functionally organized into layers. Layer four receives the densest bottom up sensory inputs, while layers 2/3 and 5 receive top down inputs that may convey predictive information. A subset of cortical somatostatin… read more here.
Keywords: cortical somatostatin; layer specific; complementary networks; networks cortical ... See more keywords