Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.25166
Abstract: Key Points Question What is the association of small vessel cerebrovascular disease, operationalized as white matter hyperintensities (WMH), with cortical thinning in a racially and ethnically diverse population of older adults? Findings In this cohort… read more here.
Keywords: cortical thinning; neurodegeneration; older adults; matter hyperintensities ... See more keywords
Differences in cortical thinning across development among individuals with and without anxiety disorders
Sign Up to like & getrecommendations! Published in 2020 at "Depression and Anxiety"
DOI: 10.1002/da.23096
Abstract: Anxiety is associated with aberrant patterns of cortical thickness in regions implicated in emotion regulation. However, few studies have examined cortical thickness differences between individuals with anxiety and healthy controls (HCs) across development, particularly during… read more here.
Keywords: anxiety; across development; differences cortical; cortical thickness ... See more keywords
Early dose-dependent cortical thinning of the femoral neck in anal cancer patients treated with pelvic radiation therapy.
Sign Up to like & getrecommendations! Published in 2017 at "Bone"
DOI: 10.1016/j.bone.2016.10.021
Abstract: BACKGROUND AND PURPOSE Anal cancer patients treated with radiation therapy (RT) have an increased risk of hip fractures after treatment. The mechanism of these fractures is unknown; however, femoral fractures have been correlated with cortical… read more here.
Keywords: radiation therapy; patients treated; anal cancer; cancer patients ... See more keywords
Cortical thinning is associated with brain pulsatility in older adults: An MRI and NIRS study
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.05.002
Abstract: Aging is accompanied by global brain atrophy occurring unequally across the brain. Cortical thinning is seen with aging with a larger loss in the frontal and temporal subregions. We explored the link between regional cortical… read more here.
Keywords: pulsatility older; pulsatility; brain pulsatility; older adults ... See more keywords
Accelerated cortical thinning within structural brain networks is associated with irritability in youth
Sign Up to like & getrecommendations! Published in 2019 at "Neuropsychopharmacology"
DOI: 10.1038/s41386-019-0508-3
Abstract: Irritability is an important dimension of psychopathology that spans multiple clinical diagnostic categories, yet its relationship to patterns of brain development remains sparsely explored. Here, we examined how transdiagnostic symptoms of irritability relate to the… read more here.
Keywords: accelerated cortical; irritability; brain networks; brain ... See more keywords
Effect of Kidney Dysfunction on Cerebral Cortical Thinning in Elderly Population
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-02537-y
Abstract: Chronic kidney disease has been linked to cognitive impairment and morphological brain change. However, less is known about the impact of kidney functions on cerebral cortical thickness. This study investigated the relationship between kidney functions… read more here.
Keywords: kidney; kidney dysfunction; elderly population; cortical thinning ... See more keywords
Cellular correlates of cortical thinning throughout the lifespan
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78471-3
Abstract: Cortical thinning occurs throughout the entire life and extends to late-life neurodegeneration, yet the neurobiological substrates are poorly understood. Here, we used a virtual-histology technique and gene expression data from the Allen Human Brain Atlas… read more here.
Keywords: gene expression; life; cellular correlates; cortical thinning ... See more keywords
APOE&egr;4 Genotype and Hypertension Modify 8-year Cortical Thinning: Five Occasion Evidence from the Seattle Longitudinal Study
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral Cortex"
DOI: 10.1093/cercor/bhx099
Abstract: We investigated individual differences in longitudinal trajectories of brain aging in cognitively normal healthy adults from the Seattle Longitudinal Study covering 8 years of longitudinal change (across 5 occasions) in cortical thickness in 249 midlife… read more here.
Keywords: cortical thinning; seattle longitudinal; thinning; hypertension ... See more keywords
No Evidence of Association between Childhood Urban Environment and Cortical Thinning in Psychotic Disorder
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0166651
Abstract: Background The alterations in cortical morphology, such as cortical thinning, observed in psychotic disorder, may be the outcome of interacting genetic and environmental effects. It has been suggested that urban upbringing may represent a proxy… read more here.
Keywords: psychotic disorder; childhood urban; disorder; group ... See more keywords
Cerebral cortical thinning in Parkinson’s disease depends on the age of onset
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0281987
Abstract: Patients with older-onset Parkinson’s disease (PD) have more severe motor symptoms, faster progression, and a worse prognosis. The thinning of the cerebral cortex is one of the causes of these issues. Patients with older-onset PD… read more here.
Keywords: disease; parkinson disease; gyrus; age onset ... See more keywords
Childhood Sexual Abuse and Cortical Thinning in Adults With Major Depressive Disorder
Sign Up to like & getrecommendations! Published in 2023 at "Psychiatry Investigation"
DOI: 10.30773/pi.2022.0314
Abstract: Objective A growing body of evidence reports on the effect of different types of childhood abuse on the structural and functional architecture of the brain. In the present study, we aimed to investigate the differences… read more here.
Keywords: childhood; abuse; depressive disorder; childhood abuse ... See more keywords