Altered cortico-striatal functional connectivity in people with high levels of schizotypy: A longitudinal resting-state study.
Sign Up to like & getrecommendations! Published in 2021 at "Asian journal of psychiatry"
DOI: 10.1016/j.ajp.2021.102621
Abstract: PURPOSE OF THE RESEARCH Cortico-striatal functional connectivity has been implicated in the neuropathology of schizophrenia. However, the longitudinal relationship between the cortico-striatal connectivity and schizotypy remains unknown. We examined the resting-state fMRI connectivity in 27… read more here.
Keywords: striatal functional; connectivity; striatal connectivity; resting state ... See more keywords
P35. Cortico-striatal functional connectivity in Huntington’s disease measured with high-field functional MRI: A biomarker for disease progression?
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2018.04.675
Abstract: Background Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by CAG expansion in the Huntingtin gene. HD manifests by involuntary movements, cognitive and behavioral changes. The approximate time-to-onset can be predicted from the length… read more here.
Keywords: striatal functional; disease; disease progression; cortico striatal ... See more keywords
Gene expression links functional networks across cortex and striatum
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03811-x
Abstract: The human brain is comprised of a complex web of functional networks that link anatomically distinct regions. However, the biological mechanisms supporting network organization remain elusive, particularly across cortical and subcortical territories with vastly divergent… read more here.
Keywords: cortico striatal; expression; gene expression; functional networks ... See more keywords
Impaired cortico-striatal excitatory transmission triggers epilepsy
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09954-9
Abstract: STXBP1 and SCN2A gene mutations are observed in patients with epilepsies, although the circuit basis remains elusive. Here, we show that mice with haplodeficiency for these genes exhibit absence seizures with spike-and-wave discharges (SWDs) initiated… read more here.
Keywords: transmission; transmission triggers; mice; cortico striatal ... See more keywords
Cortico‐striatal functional connectivity and cerebral small vessel disease: Contribution to mild Parkinsonian signs
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimaging"
DOI: 10.1111/jon.12949
Abstract: Mild Parkinsonian signs (MPS) are common in older adults. We hypothesized that MPS are associated with lower functional connectivity (FC) in dopamine‐dependent cortico‐striatal networks, and these associations vary with white matter hyperintensity (WMH), a risk… read more here.
Keywords: mild parkinsonian; cortico striatal; functional connectivity; striatal functional ... See more keywords
Cortico-striatal circuits for bilaterally coordinated movements
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abk2241
Abstract: Movement initiation and control require the orchestrated activity of sensorimotor cortical and subcortical regions. However, the exact contribution of specific pathways and interactions to the final behavioral outcome are still under debate. Here, by combining… read more here.
Keywords: circuits bilaterally; striatal circuits; movement; coordinated movements ... See more keywords
Thalamic deep brain stimulation paradigm to reduce consciousness: Cortico-striatal dynamics implicated in mechanisms of consciousness
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Computational Biology"
DOI: 10.1371/journal.pcbi.1010294
Abstract: Anesthetic manipulations provide much-needed causal evidence for neural correlates of consciousness, but non-specific drug effects complicate their interpretation. Evidence suggests that thalamic deep brain stimulation (DBS) can either increase or decrease consciousness, depending on the… read more here.
Keywords: consciousness; thalamic deep; deep brain; cortico striatal ... See more keywords
Amygdala Atrophy and Its Functional Disconnection with the Cortico-Striatal-Pallidal-Thalamic Circuit in Major Depressive Disorder in Females
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0168239
Abstract: Background Major depressive disorder (MDD) is approximately twice as common in females than males. Furthermore, female patients with MDD tend to manifest comorbid anxiety. Few studies have explored the potential anatomical and functional brain changes… read more here.
Keywords: striatal pallidal; seed; anxiety; connectivity ... See more keywords
Case Report of Dual-Site Neurostimulation and Chronic Recording of Cortico-Striatal Circuitry in a Patient With Treatment Refractory Obsessive Compulsive Disorder
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Human Neuroscience"
DOI: 10.3389/fnhum.2020.569973
Abstract: Psychiatric disorders are increasingly understood as dysfunctions of hyper- or hypoconnectivity in distributed brain circuits. A prototypical example is obsessive compulsive disorder (OCD), which has been repeatedly linked to hyper-connectivity of cortico-striatal-thalamo-cortical (CSTC) loops. Deep… read more here.
Keywords: stimulation; cortico striatal; compulsive disorder; obsessive compulsive ... See more keywords