Evaluation of Plasmapheresis vs Immunoglobulin as First Treatment After Ineffective Systemic Corticosteroid Therapy for Patients With Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2023.0035
Abstract: Importance Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are severe cutaneous adverse reactions, and patients with SJS/TEN frequently require intensive care. However, there is limited evidence on the clinical outcomes of immunomodulating therapy, including plasmapheresis… read more here.
Keywords: corticosteroid therapy; plasmapheresis; therapy; systemic corticosteroid ... See more keywords
Assessment of Corticosteroid Therapy and Death or Disability According to Pretreatment Risk of Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.12277
Abstract: This cohort study examines the association between postnatal corticosteroid therapy to prevent bronchopulmonary dysplasia (BPD) and risk of death or neurodevelopmental impairment and death or cerebral palsy in infants born at less than 27 weeks’… read more here.
Keywords: death; corticosteroid therapy; risk death; bronchopulmonary dysplasia ... See more keywords
Multiomic analysis identifies natural intrapatient temporal variability and changes in response to systemic corticosteroid therapy in chronic rhinosinusitis
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1002/iid3.349
Abstract: The pathophysiology and temporal dynamics of affected tissues in chronic rhinosinusitis (CRS) remain poorly understood. Here, we present a multiomics‐based time‐series assessment of nasal polyp biopsies from three patients with CRS, assessing natural variability over… read more here.
Keywords: chronic rhinosinusitis; variability; systemic corticosteroid; response systemic ... See more keywords
Effect of corticosteroid therapy on mortality in COVID‐19 patients—A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.2386
Abstract: The effect of corticosteroid therapy is still controversial on prevention of mortality in coronavirus disease‐2019 (COVID‐19). The objective of this study is to investigate the effect of corticosteroids on mortality. This systematic review was performed… read more here.
Keywords: mortality; effect corticosteroid; corticosteroid therapy;
Efficacy and safety of corticosteroid therapy in patients with cardiac arrest: a systematic review of randomised controlled trials
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Clinical Pharmacology"
DOI: 10.1007/s00228-020-02964-3
Abstract: The role of corticosteroid therapy in patients with cardiac arrest (CA) is uncertain. We aimed to evaluate the efficacy and safety of corticosteroid therapy in CA patients. Randomised controlled trials were identified using PubMed, EMBASE,… read more here.
Keywords: patients cardiac; cardiac arrest; therapy patients; therapy ... See more keywords
Intensified adjunctive corticosteroid therapy for CNS tuberculomas
Sign Up to like & getrecommendations! Published in 2020 at "Infection"
DOI: 10.1007/s15010-019-01378-3
Abstract: Introduction Central nervous system (CNS) tuberculomas are a challenging manifestation of extrapulmonary tuberculosis often leading to neurological complications and post-treatment sequelae. The role of adjunctive corticosteroid treatment is not fully understood. Most guidelines on management… read more here.
Keywords: corticosteroid therapy; tuberculomas; adjunctive corticosteroid; cns tuberculomas ... See more keywords
[Impact of the use of systemic corticosteroid therapy on the effectiveness of immune checkpoint inhibitors].
Sign Up to like & getrecommendations! Published in 2021 at "Bulletin du cancer"
DOI: 10.1016/j.bulcan.2021.01.015
Abstract: Immunotherapy, which consists in using molecules targeting the immune system, has existed for many years in oncology (vaccines, interleukins, monoclonal antibodies) but has recently expanded due to the development of immune checkpoint inhibitors. These monoclonal… read more here.
Keywords: use systemic; immune checkpoint; checkpoint inhibitors; corticosteroid therapy ... See more keywords
Corticosteroid Therapy Is Associated With Improved Outcome in Critically Ill Patients With COVID-19 With Hyperinflammatory Phenotype
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DOI: 10.1016/j.chest.2020.11.050
Abstract: Background Corticosteroid therapy is used commonly in patients with coronavirus disease 2019 (COVID-19), although its impact on outcomes and which patients could benefit from corticosteroid therapy are uncertain. Research Question Are clinical phenotypes of COVID-19… read more here.
Keywords: therapy associated; ill patients; critically ill; hyperinflammatory phenotype ... See more keywords
The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19
Sign Up to like & getrecommendations! Published in 2021 at "Computational Biology and Chemistry"
DOI: 10.1016/j.compbiolchem.2021.107482
Abstract: Complement system plays a dual role; physiological as well as pathophysiological. While physiological role protects the host, pathophysiological role can substantially harm the host, by triggering several hyper-inflammatory pathways, referred as “hypercytokinaemia”. Emerging clinical evidence… read more here.
Keywords: management; role; c5a; severe covid19 ... See more keywords
Rapid biophysical analyses of gastric aspirates from risk newborns for lung maturity assessment after corticosteroid therapy
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e03072
Abstract: Background One of the main causes for the higher mortality among risk newborn children (including preterm infants) is neonatal respiratory distress syndrome (NRDS), which develops as a result of primary deficiency or secondary inactivation of… read more here.
Keywords: therapy; corticosteroid therapy; risk; lung maturity ... See more keywords
Impact of early initiation of corticosteroid therapy on cardiac function and rhythm in patients with cardiac sarcoidosis.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2016.10.101
Abstract: BACKGROUND There is limited data on the effect of corticosteroid therapy in patients with cardiac sarcoidosis (CS). We sought to examine the impact of early initiation of corticosteroid therapy, within a month of CS diagnosis,… read more here.
Keywords: therapy; corticosteroid therapy; initiation corticosteroid; early initiation ... See more keywords