Long-Term Survival After Transformation of an Adrenocorticotropic Hormone-Secreting Pituitary Macroadenoma to a Silent Corticotroph Pituitary Carcinoma.
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DOI: 10.1016/j.wneu.2018.11.011
Abstract: BACKGROUND Pituitary carcinomas are rare and aggressive neoplasms that despite current treatment regimens continue to have a poor prognosis. Adrenocorticotrophic hormone pituitary tumors have been shown to alter their clinical manifestations with conversion to Cushing… read more here.
Keywords: hormone; silent corticotroph; hormone secreting; secreting pituitary ... See more keywords
MON-406 Two Cases of Aggressive Corticotroph Pituitary Tumors Treated with Capecitabine and Temozolomide
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DOI: 10.1210/js.2019-mon-406
Abstract: Abstract Introduction: Aggressive corticotroph tumors exhibit continued growth despite multimodal therapy, including surgeries, radiotherapy and/or medical treatment. Temozolomide (TMZ), an oral alkylating agent, has been used to treat aggressive pituitary tumors; however, most patients only… read more here.
Keywords: therapy; corticotroph; corticotroph pituitary; surgery ... See more keywords
Surgical Outcomes of Silent ACTH+ Corticotroph Pituitary Neuroendocrine Tumors: A Multi-Institutional Experience and Review of the Literature.
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DOI: 10.1227/neu.0000000000003512
Abstract: BACKGROUND AND OBJECTIVES Silent corticotroph pituitary neuroendocrine tumors (PitNETs) constitute approximately 20% of nonfunctional PitNETs and exhibit positive immunostaining for adrenocorticotropic hormone (ACTH). These tumors have been characterized as exhibiting high recurrence rates and poor… read more here.
Keywords: silent corticotroph; pituitary neuroendocrine; corticotroph; corticotroph pituitary ... See more keywords