Gamma knife radiosurgery in patients with Cushing’s disease: Comparison of aggressive pituitary corticotroph tumor versus corticotroph adenoma
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2020.106151
Abstract: Aggressive pituitary corticotroph tumors causing Cushing's disease are rare, and there is limited data about their clinical management. Here, we aimed to report our long-term experience with gamma knife radiosurgery (GKRS) as adjuvant treatment in… read more here.
Keywords: cushing disease; aggressive pituitary; pituitary corticotroph; corticotroph tumors ... See more keywords
Single Cell RNA Sequencing in Silent Corticotroph Tumors Confirms Impaired POMC Processing and Provides New Insights into Their Invasive Behavior.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-21-1183
Abstract: OBJECTIVE Provide insights into the defective POMC processing and invasive behavior in silent pituitary corticotroph tumors. DESIGN AND METHODS Single cell RNAseq was used to compare the cellular makeup and transcriptome of silent and active… read more here.
Keywords: cell; corticotroph tumors; corticotroph; silent corticotroph ... See more keywords
The expression of glucocorticoid and mineralocorticoid receptors in pituitary tumors causing Cushing’s disease and silent corticotroph tumors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1124646
Abstract: Objective Pituitary neuroendocrine corticotroph tumors commonly cause Cushing’s disease (CD) that results from increased adrenocorticotropic hormone (ACTH) secretion by the pituitary tumor and consequent increase of cortisol levels in blood. However, in some patients, corticotroph… read more here.
Keywords: glucocorticoid mineralocorticoid; expression; corticotroph tumors; silent corticotroph ... See more keywords