Reduced Numbers of Corticotropin‐Releasing Hormone Neurons in Narcolepsy Type 1
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26300
Abstract: Narcolepsy type 1 (NT1) is a chronic sleep disorder correlated with loss of hypocretin(orexin). In NT1 post‐mortem brains, we observed 88% reduction in corticotropin‐releasing hormone (CRH)‐positive neurons in the paraventricular nucleus (PVN) and significantly less… read more here.
Keywords: releasing hormone; hormone; corticotropin releasing; numbers corticotropin ... See more keywords
Effects of early trauma and corticotropin‐releasing factor receptor 1 gene polymorphism on adult visual spatial memory
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.974
Abstract: The study sought to determine the effects of earthquake on the working memory of adults who experienced earthquake either as infants or fetuses and also investigates whether earthquake exposure and corticotropin‐releasing factor receptor 1 (CRHR1)… read more here.
Keywords: factor receptor; releasing factor; corticotropin releasing; memory ... See more keywords
Probing the Interactome of Corticotropin-Releasing Factor Receptor Heteromers Using Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9121-1_15
Abstract: Mass spectrometry is a sensitive technique used in the field of proteomics that allows for simultaneous detection and characterization of several proteins in a sample. It is also a powerful methodology to elucidate protein-protein interactions… read more here.
Keywords: releasing factor; mass spectrometry; corticotropin releasing; mass ... See more keywords
Cancer-Specific Loss of Urocortin 3 in Human Renal Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Advances in Therapy"
DOI: 10.1007/s12325-019-01141-y
Abstract: Introduction The corticotropin-releasing hormone (CRH) system, its receptors corticotropin-releasing hormone receptor 1 (CRHR1) and 2 (CRHR2), and its corresponding binding protein corticotropin-releasing hormone-binding protein (CRHBP) as well as the urocortin proteins—structural homologues to CRH, which… read more here.
Keywords: ucn3 mrna; releasing hormone; cancer specific; corticotropin releasing ... See more keywords
Evidence that preimmunization with a heat-killed preparation of Mycobacterium vaccae reduces corticotropin-releasing hormone mRNA expression in the extended amygdala in a fear-potentiated startle paradigm
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.12.015
Abstract: Posttraumatic stress disorder (PTSD) is a trauma and stressor-related disorder that is characterized by dysregulation of glucocorticoid signaling, chronic low-grade inflammation, and impairment in the ability to extinguish learned fear. Corticotropin-releasing hormone (Crh) is a… read more here.
Keywords: preimmunization; fear; corticotropin releasing; vaccae ... See more keywords
Abandoned prairie vole mothers show normal maternal care but altered emotionality: Potential influence of the brain corticotropin-releasing factor system
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.12.034
Abstract: HighlightsAbandoned mothers often suffer from emotional dysfunctions.Prairie voles serve as animal model to study biparental care and partner loss.Separated vole mothers showed normal maternal care but increased emotionality.Separation increased CRF mRNA expression in the PVN.Acute… read more here.
Keywords: prairie vole; normal maternal; corticotropin releasing; vole mothers ... See more keywords
The role of peripheral corticotropin-releasing factor signaling in a rat model of stress-induced gastric hyperalgesia.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.040
Abstract: BACKGROUND Functional dyspepsia (FD) is a common gastrointestinal disorder associated with persistent or recurrent upper gastrointestinal tract symptoms such as pain without any obvious pathological changes. Psychological and psychiatric factors might have a pathogenic role… read more here.
Keywords: corticotropin releasing; hyperalgesia; gastric hyperalgesia; crf2 ... See more keywords
Spexin as an anxiety regulator in mouse hippocampus: Mechanisms for transcriptional regulation of spexin gene expression by corticotropin releasing factor.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.023
Abstract: Spexin (SPX) acts as a neuropeptide with pleiotropic functions that can participate in anxiety regulation. Corticotropin releasing factor (CRF) is widely expressed in brain tissues and associated with depression and anxiety and addiction. With the… read more here.
Keywords: releasing factor; spexin; anxiety; corticotropin releasing ... See more keywords
Activating Corticotropin-Releasing Factor Systems in the Nucleus Accumbens, Amygdala, and Bed Nucleus of Stria Terminalis: Incentive Motivation or Aversive Motivation?
Sign Up to like & getrecommendations! Published in 2021 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2021.01.007
Abstract: BACKGROUND Corticotropin-releasing factor (CRF) neural systems are important stress mechanisms in the central amygdala (CeA), bed nucleus of stria terminalis (BNST), nucleus accumbens (NAc), and related structures. CRF-containing neural systems are traditionally posited to generate… read more here.
Keywords: stimulation; corticotropin releasing; incentive motivation; crf containing ... See more keywords
Antagonism of corticotropin‐releasing factor CRF1 receptors blocks the enhanced response to cocaine after social stress
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.01.052
Abstract: Abstract Numerous studies have shown that social defeat stress induces an increase in the rewarding effects of cocaine. In this study we have investigated the role played by the main hypothalamic stress hormone, corticotropin‐releasing factor… read more here.
Keywords: cocaine; stress; corticotropin releasing; releasing factor ... See more keywords
Prenatal betamethasone exposure increases corticotropin-releasing hormone expression along with increased hippocampal slice excitability in the developing hippocampus
Sign Up to like & getrecommendations! Published in 2020 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2020.106276
Abstract: BACKGROUND The objective of this study was to determine whether prenatal exposure to betamethasone alters hippocampal expression of corticotropin-releasing hormone (CRH) and resultant hippocampal circuit excitability. METHODS Real time (RT)-PCR and western blots were used… read more here.
Keywords: corticotropin releasing; exposure; betamethasone; crh ... See more keywords