Associations of age, BMI, and renal function to cortisol after dexamethasone suppression in patients with adrenal incidentalomas
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DOI: 10.3389/fendo.2022.1055298
Abstract: Introduction The specificity of cortisol after 1 mg dexamethasone (cortisolDST) ≥50 nmol/L as a criterion for mild autonomous cortisol secretion (MACS) is approximately 85% in patients with adrenal incidentalomas (AI). The aim was to study… read more here.
Keywords: cortisol dexamethasone; age bmi; patients adrenal; age ... See more keywords
Glucocorticoids Bind to SARS-CoV-2 S1 at Multiple Sites Causing Cooperative Inhibition of SARS-CoV-2 S1 Interaction With ACE2
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DOI: 10.3389/fimmu.2022.906687
Abstract: Dexamethasone may reduce mortality in COVID-19 patients. Whether dexamethasone or endogenous glucocorticoids, such as cortisol, biochemically interact with SARS-CoV-2 spike 1 protein (S1), or its cellular receptor ACE2, is unknown. Using molecular dynamics (MD) simulations… read more here.
Keywords: cortisol dexamethasone; interaction; interaction ace2; sars cov ... See more keywords