Bioanalytical method development and validation of corynantheidine, a kratom alkaloid, using UPLC-MS/MS, and its application to preclinical pharmacokinetic studies.
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DOI: 10.1016/j.jpba.2019.113019
Abstract: Corynantheidine, a minor alkaloid found in Mitragyna speciosa (Korth.) Havil, has been shown to bind to opioid receptors and act as a functional opioid antagonist, but its unique contribution to the overall properties of kratom… read more here.
Keywords: corynantheidine; method development; pharmacokinetic studies; analysis ... See more keywords