Corynoxine B derivative CB6 prevents Parkinsonian toxicity in mice by inducing PIK3C3 complex-dependent autophagy.
Sign Up to like & getrecommendations! Published in 2022 at "Acta pharmacologica Sinica"
DOI: 10.1038/s41401-022-00871-0
Abstract: Increasing evidence shows that autophagy impairment is involved in the pathogenesis and progression of neurodegenerative diseases including Parkinson's disease (PD). We previously identified a natural alkaloid named corynoxine B (Cory B) as a neuronal autophagy… read more here.
Keywords: corynoxine derivative; pik3c3 complex; cb6; autophagy ... See more keywords