Articles with "cost" as a keyword



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Cost-effectiveness of Canakinumab for Prevention of Recurrent Cardiovascular Events

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Published in 2019 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2018.4566

Abstract: Importance In the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial, the anti-inflammatory monoclonal antibody canakinumab significantly reduced the risk of recurrent cardiovascular events in patients with previous myocardial infarction (MI) and high-sensitivity C-reactive protein (hs-CRP)… read more here.

Keywords: cost effectiveness; recurrent cardiovascular; canakinumab; cardiovascular events ... See more keywords
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Metabolic Cost of Exercise Initiation in Patients With Heart Failure With Preserved Ejection Fraction vs Community-Dwelling Adults.

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Published in 2021 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.0292

Abstract: Importance Heart failure with preserved ejection fraction (HFpEF) is a joint metabolic and cardiovascular disorder with significant noncardiac contributions. Objective To define and quantify the metabolic cost of initiating exercise in individuals with and without… read more here.

Keywords: interquartile range; community; community dwelling; exercise ... See more keywords
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Evaluation of Factors Underlying Sex-Based Disparities in Cardiovascular Care in Adults With Self-reported Premature Atherosclerotic Cardiovascular Disease.

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Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.5430

Abstract: Importance There are limited data regarding sex-based differences in physical and mental health domains and health care access in adults with premature atherosclerotic cardiovascular disease (ASCVD). Objective To study the association of sex with physical… read more here.

Keywords: health; reported premature; cost; self reported ... See more keywords
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Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for the Treatment of Heart Failure With Preserved Ejection Fraction.

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Published in 2023 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2023.0077

Abstract: Importance Adding a sodium-glucose cotransporter-2 inhibitor (SGLT2-I) to standard-of-care treatment in patients with heart failure with preserved ejection fraction (HFpEF) reduces the risk of a composite outcome of worsening heart failure or cardiovascular mortality, but… read more here.

Keywords: heart failure; cost; care; standard care ... See more keywords
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Economic Evaluation of Talimogene Laherparepvec Plus Ipilimumab Combination Therapy vs Ipilimumab Monotherapy in Patients With Advanced Unresectable Melanoma

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Published in 2019 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.3958

Abstract: Importance A phase 2 trial comparing talimogene laherparepvec plus ipilimumab vs ipilimumab monotherapy in patients with advanced unresectable melanoma found no differential benefit in progression-free survival (PFS) but noted objective response rates (ORRs) of 38.8%… read more here.

Keywords: talimogene laherparepvec; life; laherparepvec plus; plus ipilimumab ... See more keywords
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Cost-Utility Analysis of Rituximab vs Mycophenolate Mofetil for the Treatment of Pemphigus Vulgaris.

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Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.2878

Abstract: Importance There is an increasing body of literature that supports the use of rituximab as a first-line steroid-sparing agent in pemphigus vulgaris. However, the cost of rituximab is substantial compared with conventional agents, and there… read more here.

Keywords: rituximab biosimilars; cost; pemphigus vulgaris; mycophenolate mofetil ... See more keywords
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Cost-effectiveness of Response-Adapted De-escalation of Immunotherapy in Advanced Melanoma.

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Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.4556

Abstract: Importance Combination immunotherapy with nivolumab and ipilimumab has markedly improved outcomes for patients with advanced melanoma. However, these therapies pose a considerable financial burden to both patients and the health care system. The ADAPT-IT trial… read more here.

Keywords: advanced melanoma; cost; response adapted; response ... See more keywords
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Cost-effectiveness of the Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults

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Published in 2018 at "JAMA Internal Medicine"

DOI: 10.1001/jamainternmed.2017.7431

Abstract: Importance The live attenuated herpes zoster vaccine (ZVL) is recommended for immunocompetent adults 60 years or older, but the efficacy wanes with age and over time. A new adjuvanted herpes zoster subunit vaccine (HZ/su) has… read more here.

Keywords: cost; herpes zoster; price; dose ... See more keywords
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Estimated Costs of Pivotal Trials for Novel Therapeutic Agents Approved by the US Food and Drug Administration, 2015-2016

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Published in 2018 at "JAMA Internal Medicine"

DOI: 10.1001/jamainternmed.2018.3931

Abstract: Importance A critical question in health care is the extent of scientific evidence that should be required to establish that a new therapeutic agent has benefits that outweigh its risks. Estimating the costs of this… read more here.

Keywords: trial; drug; million million; 2015 2016 ... See more keywords
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Use and Cost of Low-Value Health Services Delivered or Paid for by the Veterans Health Administration.

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Published in 2022 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2022.2482

Abstract: Importance Within the Veterans Health Administration (VA), the use and cost of low-value services delivered by VA facilities or increasingly by VA Community Care (VACC) programs have not been comprehensively quantified. Objective To quantify veterans'… read more here.

Keywords: health; cost; service; low value ... See more keywords
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Effects of Real-time Prescription Benefit Recommendations on Patient Out-of-Pocket Costs: A Cluster Randomized Clinical Trial.

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Published in 2022 at "JAMA internal medicine"

DOI: 10.1001/jamainternmed.2022.3946

Abstract: Importance Rising drug costs contribute to medication nonadherence and adverse health outcomes. Real-time prescription benefit (RTPB) systems present prescribers with patient-specific out-of-pocket cost estimates and recommend lower-cost, clinically appropriate alternatives at the point of prescribing.… read more here.

Keywords: prescription; cost; trial; patient pocket ... See more keywords