Articles with "cost" as a keyword



Cost-effectiveness of Canakinumab for Prevention of Recurrent Cardiovascular Events

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Published in 2019 at "JAMA Cardiology"

DOI: 10.1001/jamacardio.2018.4566

Abstract: Importance In the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial, the anti-inflammatory monoclonal antibody canakinumab significantly reduced the risk of recurrent cardiovascular events in patients with previous myocardial infarction (MI) and high-sensitivity C-reactive protein (hs-CRP)… read more here.

Keywords: cost effectiveness; recurrent cardiovascular; canakinumab; cardiovascular events ... See more keywords

Metabolic Cost of Exercise Initiation in Patients With Heart Failure With Preserved Ejection Fraction vs Community-Dwelling Adults.

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Published in 2021 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.0292

Abstract: Importance Heart failure with preserved ejection fraction (HFpEF) is a joint metabolic and cardiovascular disorder with significant noncardiac contributions. Objective To define and quantify the metabolic cost of initiating exercise in individuals with and without… read more here.

Keywords: interquartile range; community; community dwelling; exercise ... See more keywords

Evaluation of Factors Underlying Sex-Based Disparities in Cardiovascular Care in Adults With Self-reported Premature Atherosclerotic Cardiovascular Disease.

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Published in 2022 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2021.5430

Abstract: Importance There are limited data regarding sex-based differences in physical and mental health domains and health care access in adults with premature atherosclerotic cardiovascular disease (ASCVD). Objective To study the association of sex with physical… read more here.

Keywords: health; reported premature; cost; self reported ... See more keywords

Cost-effectiveness of Sodium-Glucose Cotransporter-2 Inhibitors for the Treatment of Heart Failure With Preserved Ejection Fraction.

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Published in 2023 at "JAMA cardiology"

DOI: 10.1001/jamacardio.2023.0077

Abstract: Importance Adding a sodium-glucose cotransporter-2 inhibitor (SGLT2-I) to standard-of-care treatment in patients with heart failure with preserved ejection fraction (HFpEF) reduces the risk of a composite outcome of worsening heart failure or cardiovascular mortality, but… read more here.

Keywords: heart failure; cost; care; standard care ... See more keywords

Economic Evaluation of Talimogene Laherparepvec Plus Ipilimumab Combination Therapy vs Ipilimumab Monotherapy in Patients With Advanced Unresectable Melanoma

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Published in 2019 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.3958

Abstract: Importance A phase 2 trial comparing talimogene laherparepvec plus ipilimumab vs ipilimumab monotherapy in patients with advanced unresectable melanoma found no differential benefit in progression-free survival (PFS) but noted objective response rates (ORRs) of 38.8%… read more here.

Keywords: talimogene laherparepvec; life; laherparepvec plus; plus ipilimumab ... See more keywords

Cost-Utility Analysis of Rituximab vs Mycophenolate Mofetil for the Treatment of Pemphigus Vulgaris.

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Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.2878

Abstract: Importance There is an increasing body of literature that supports the use of rituximab as a first-line steroid-sparing agent in pemphigus vulgaris. However, the cost of rituximab is substantial compared with conventional agents, and there… read more here.

Keywords: rituximab biosimilars; cost; pemphigus vulgaris; mycophenolate mofetil ... See more keywords

Cost-effectiveness of Response-Adapted De-escalation of Immunotherapy in Advanced Melanoma.

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Published in 2022 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2022.4556

Abstract: Importance Combination immunotherapy with nivolumab and ipilimumab has markedly improved outcomes for patients with advanced melanoma. However, these therapies pose a considerable financial burden to both patients and the health care system. The ADAPT-IT trial… read more here.

Keywords: advanced melanoma; cost; response adapted; response ... See more keywords

Use of Efficiency Frontiers to Align Prices and Clinical Benefits of Biologic Therapies for Plaque Psoriasis.

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Published in 2024 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2023.6236

Abstract: Importance The US lacks a systematic approach for aligning drug prices with clinical benefit, and traditional cost-effectiveness analysis (CEA) faces political obstacles. The efficiency frontier (EF) method offers policymakers an alternative approach. Objective To assess… read more here.

Keywords: plaque psoriasis; clinical benefits; prices clinical; cost ... See more keywords

Economic Evaluation of HLA-B*15:02 Genotyping for Asian Australian Patients With Epilepsy.

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Published in 2024 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2024.1037

Abstract: Importance The HLA-B*15:02 allele has been associated with an increased risk of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in specific Asian populations (including Han Chinese, Malaysian, Thai, and Vietnamese individuals). While HLA-B*15:02 genotype testing… read more here.

Keywords: asian australian; hla; genotyping asian; hla genotyping ... See more keywords

Cost-Effectiveness Analysis of 3D Total-Body Photography for People at High Risk of Melanoma.

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Published in 2025 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2025.0219

Abstract: Importance Greater use of novel digital technologies could be associated with improved health outcomes and save health care costs by detecting smaller melanomas earlier (needing less treatment) or benign tumors (needing no treatment). Objective To… read more here.

Keywords: care; melanoma; high risk; cost ... See more keywords

Cost-effectiveness of the Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults

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Published in 2018 at "JAMA Internal Medicine"

DOI: 10.1001/jamainternmed.2017.7431

Abstract: Importance The live attenuated herpes zoster vaccine (ZVL) is recommended for immunocompetent adults 60 years or older, but the efficacy wanes with age and over time. A new adjuvanted herpes zoster subunit vaccine (HZ/su) has… read more here.

Keywords: cost; herpes zoster; price; dose ... See more keywords