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Published in 2019 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2018.4566
Abstract: Importance In the Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial, the anti-inflammatory monoclonal antibody canakinumab significantly reduced the risk of recurrent cardiovascular events in patients with previous myocardial infarction (MI) and high-sensitivity C-reactive protein (hs-CRP)…
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Keywords:
cost effectiveness;
recurrent cardiovascular;
canakinumab;
cardiovascular events ... See more keywords
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Published in 2021 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.0292
Abstract: Importance Heart failure with preserved ejection fraction (HFpEF) is a joint metabolic and cardiovascular disorder with significant noncardiac contributions. Objective To define and quantify the metabolic cost of initiating exercise in individuals with and without…
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Keywords:
interquartile range;
community;
community dwelling;
exercise ... See more keywords
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Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2021.5430
Abstract: Importance There are limited data regarding sex-based differences in physical and mental health domains and health care access in adults with premature atherosclerotic cardiovascular disease (ASCVD). Objective To study the association of sex with physical…
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Keywords:
health;
reported premature;
cost;
self reported ... See more keywords
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Published in 2023 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2023.0077
Abstract: Importance Adding a sodium-glucose cotransporter-2 inhibitor (SGLT2-I) to standard-of-care treatment in patients with heart failure with preserved ejection fraction (HFpEF) reduces the risk of a composite outcome of worsening heart failure or cardiovascular mortality, but…
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Keywords:
heart failure;
cost;
care;
standard care ... See more keywords
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Published in 2019 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.3958
Abstract: Importance A phase 2 trial comparing talimogene laherparepvec plus ipilimumab vs ipilimumab monotherapy in patients with advanced unresectable melanoma found no differential benefit in progression-free survival (PFS) but noted objective response rates (ORRs) of 38.8%…
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Keywords:
talimogene laherparepvec;
life;
laherparepvec plus;
plus ipilimumab ... See more keywords
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Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.2878
Abstract: Importance There is an increasing body of literature that supports the use of rituximab as a first-line steroid-sparing agent in pemphigus vulgaris. However, the cost of rituximab is substantial compared with conventional agents, and there…
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Keywords:
rituximab biosimilars;
cost;
pemphigus vulgaris;
mycophenolate mofetil ... See more keywords
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Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2022.4556
Abstract: Importance Combination immunotherapy with nivolumab and ipilimumab has markedly improved outcomes for patients with advanced melanoma. However, these therapies pose a considerable financial burden to both patients and the health care system. The ADAPT-IT trial…
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Keywords:
advanced melanoma;
cost;
response adapted;
response ... See more keywords
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Published in 2018 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2017.7431
Abstract: Importance The live attenuated herpes zoster vaccine (ZVL) is recommended for immunocompetent adults 60 years or older, but the efficacy wanes with age and over time. A new adjuvanted herpes zoster subunit vaccine (HZ/su) has…
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Keywords:
cost;
herpes zoster;
price;
dose ... See more keywords
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Published in 2018 at "JAMA Internal Medicine"
DOI: 10.1001/jamainternmed.2018.3931
Abstract: Importance A critical question in health care is the extent of scientific evidence that should be required to establish that a new therapeutic agent has benefits that outweigh its risks. Estimating the costs of this…
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Keywords:
trial;
drug;
million million;
2015 2016 ... See more keywords
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Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.2482
Abstract: Importance Within the Veterans Health Administration (VA), the use and cost of low-value services delivered by VA facilities or increasingly by VA Community Care (VACC) programs have not been comprehensively quantified. Objective To quantify veterans'…
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Keywords:
health;
cost;
service;
low value ... See more keywords
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Published in 2022 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2022.3946
Abstract: Importance Rising drug costs contribute to medication nonadherence and adverse health outcomes. Real-time prescription benefit (RTPB) systems present prescribers with patient-specific out-of-pocket cost estimates and recommend lower-cost, clinically appropriate alternatives at the point of prescribing.…
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Keywords:
prescription;
cost;
trial;
patient pocket ... See more keywords