Porcine NK cells display features associated with antigen‐presenting cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4a0417-163rr
Abstract: NK cells are members of the innate immunity and play a central role in the defense against viral infections and cancer development, but also contribute to triggering and shaping adaptive immune responses. Human NK cells… read more here.
Keywords: cell; express mhc; porcine cells; costimulatory molecules ... See more keywords
Fc-based Duokines: dual-acting costimulatory molecules comprising TNFSF ligands in the single-chain format fused to a heterodimerizing Fc (scDk-Fc)
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2028961
Abstract: ABSTRACT Targeting costimulatory receptors of the tumor necrosis factor superfamily (TNFSF) to activate T-cells and promote anti-tumor T-cell function have emerged as a promising strategy in cancer immunotherapy. Previous studies have shown that combining two… read more here.
Keywords: cell; dual acting; single chain; acting costimulatory ... See more keywords
Neuroimmune semaphorins as costimulatory molecules and beyond
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Medicine"
DOI: 10.1186/s10020-018-0014-9
Abstract: Several neuronal guidance proteins, known as semaphorin molecules, function in the immune system. This dual tissue performance has led to them being defined as “neuroimmune semaphorins”. They have been shown to regulate T cell activation… read more here.
Keywords: neuroimmune semaphorins; cell; molecules beyond; costimulatory molecules ... See more keywords
The role of costimulatory molecules in glioma biology and immune microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1024922
Abstract: Background: Extensive research showed costimulatory molecules regulate tumor progression. Nevertheless, a small amount of literature has concentrated on the potential prognostic and therapeutic effects of costimulatory molecules in patients with glioma. Methods: The data were… read more here.
Keywords: high risk; risk group; analysis; costimulatory molecules ... See more keywords
A novel diagnostic model for predicting immune microenvironment subclass based on costimulatory molecules in lung squamous carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1078790
Abstract: There is still no ideal predictive biomarker for immunotherapy response among patients with non-small cell lung cancer. Costimulatory molecules play a role in anti-tumor immune response. Hence, they can be a potential biomarker for immunotherapy… read more here.
Keywords: microenvironment; squamous carcinoma; molecules lung; costimulatory ... See more keywords
A Signature Based on Costimulatory Molecules for the Assessment of Prognosis and Immune Characteristics in Patients With Stomach Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.928742
Abstract: Although costimulatory molecules have been shown to boost antitumor immune responses, their significance in stomach adenocarcinoma (STAD) remains unknown. The purpose of this study was to examine the gene expression patterns of costimulatory molecule genes… read more here.
Keywords: prognosis; signature; stomach adenocarcinoma; costimulatory ... See more keywords
Kinetic Changes in B7 Costimulatory Molecules and IRF4 Expression in Human Dendritic Cells during LPS Exposure
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12070955
Abstract: A key aspect of the inflammatory phenomenon is the involvement of costimulatory molecules expressed by antigen-presenting cells (APCs) and their ability to secrete cytokines to set instructions for an adaptive immune response and to generate… read more here.
Keywords: kinetic changes; expression; changes costimulatory; molecules irf4 ... See more keywords