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Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.251
Abstract: 251Background: Palbociclib, a CDK4/6 inhibitor, blocked proliferation and promoted G1 arrest in an Rb and Cyclin D dependent manner in preclinical models of HSPC. Alterations in this pathway contribute to the development of CRPC. We…
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Keywords:
cell cycle;
signaling cell;
cotargeting signaling;
therapy ... See more keywords