The association of in utero tobacco smoke exposure, quantified by serum cotinine, and Autism Spectrum Disorder
Sign Up to like & getrecommendations! Published in 2021 at "Autism Research"
DOI: 10.1002/aur.2561
Abstract: Previous studies on in utero exposure to maternal environmental tobacco smoke (ETS) or maternal active smoking and Autism Spectrum Disorder (ASD) have not been entirely consistent, and no studies have examined in utero cotinine concentrations… read more here.
Keywords: autism; exposure; cotinine; tobacco smoke ... See more keywords
Modification of adverse health effects of maternal active and passive smoking by genetic susceptibility: Dose-dependent association of plasma cotinine with infant birth size among Japanese women-The Hokkaido Study.
Sign Up to like & getrecommendations! Published in 2017 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2017.09.002
Abstract: OBJECTIVES We aimed to assess the individual dose-response effects of eight maternal polymorphisms encoding polycyclic aromatic hydrocarbon-metabolizing and DNA-repair genes on prenatal cotinine levels according to infant birth size. METHODS In total, 3263 Japanese pregnant… read more here.
Keywords: infant birth; birth; cotinine; dose dependent ... See more keywords
One-Shot In Vitro Evolution Generated an Antibody Fragment for Testing Urinary Cotinine with More Than 40-Fold Enhanced Affinity.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.6b04332
Abstract: Immunoassays for cotinine, a major nicotine metabolite, in the urine are useful for monitoring the degree of tobacco smoke exposure. However, hybridoma-based anti-cotinine antibodies lack sufficient binding affinity to perform practically sensitive measurements, and thus… read more here.
Keywords: urinary cotinine; vitro evolution; one shot; cotinine ... See more keywords
Disruption of retinal pigment epithelial cell properties under the exposure of cotinine
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-03283-x
Abstract: Cigarette smoking is a major risk factor for age-related macular degeneration (AMD), in which progressive retinal pigment epithelial (RPE) cell degeneration is a major pathological change. Nicotine is a major biologically active component in cigarette… read more here.
Keywords: rpe cell; pigment epithelial; cotinine; retinal pigment ... See more keywords
The effects of amniotic fluid and foetal cord blood cotinine concentrations on pregnancy complications and the anthropometric measurements of newborns
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2019.1599834
Abstract: Abstract Our objective was determining the effects of amniotic fluid (AF) and fetal cord blood (FCB) cotinine concentrations on pregnancy complications and the anthropometric measurements in the newborns whose mothers underwent amniocentesis. This study was… read more here.
Keywords: anthropometric measurements; cotinine levels; cord blood; pregnancy complications ... See more keywords
P4390Sex-specific association between secondhand smoke exposure and metabolic syndrome in 118,609 Korean never-smokers verified by both self-reported questionnaire and cotinine
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.0795
Abstract: No study has reported the relationship between secondhand smoke (SHS) exposure and metabolic syndrome (MetS) in self-reported never-smokers verified by nicotine metabolite. The aim of this study is to determine the relationship between SHS exposure… read more here.
Keywords: shs exposure; never smokers; exposure; cotinine ... See more keywords
Association between smoking status assessed with plasma‐cotinine and inflammatory and endothelial biomarkers in HIV‐positive and HIV‐negative individuals
Sign Up to like & getrecommendations! Published in 2018 at "HIV Medicine"
DOI: 10.1111/hiv.12647
Abstract: Smoking is a major contributor to mortality and morbidity in HIV‐positive individuals. Our primary objective was to evaluate the association between smoking status determined by plasma cotinine (P‐cotinine) concentration and inflammatory and endothelial biomarkers in… read more here.
Keywords: inflammatory endothelial; cotinine; smoking status; plasma cotinine ... See more keywords
CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine
Sign Up to like & getrecommendations! Published in 2022 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.121.000624
Abstract: The primary mode of metabolism of nicotine is via the formation of cotinine by the enzyme CYP2A6. Cotinine undergoes further CYP2A6-mediated metabolism by hydroxylation to 3-hydroxycotinine and norcotinine, but can also form cotinine-N-glucuronide and cotinine-N-oxide… read more here.
Keywords: oxidation; cox formation; genetic variants; cotinine ... See more keywords
Suboptimal vitamin D status in Korean adolescents: a nationwide study on its prevalence, risk factors including cotinine-verified smoking status and association with atopic dermatitis and asthma
Sign Up to like & getrecommendations! Published in 2017 at "BMJ Open"
DOI: 10.1136/bmjopen-2017-016409
Abstract: Objective To determine the prevalence and risk factors for suboptimal vitamin D status in Korean adolescents and to assess its relationship with atopic dermatitis (AD) and asthma at a national level. Design This is a… read more here.
Keywords: status; korean adolescents; cotinine; prevalence ... See more keywords
1453 Urinary cotinine in tobacco farmers in southern brazil
Sign Up to like & getrecommendations! Published in 2018 at "Occupational and Environmental Medicine"
DOI: 10.1136/oemed-2018-icohabstracts.1140
Abstract: Introduction High levels of cotinine have been related to the occurrence of green tobacco sickness (GTS), however chronic exposure to nicotine develops tolerance. The objective of this paper is to describe urinary cotinine levels in… read more here.
Keywords: urinary cotinine; tobacco; cotinine; cotinine means ... See more keywords
S52 Self-reported smoking abstinence in potential lung (LTx) and heart transplant (HTx) candidates: unbelievable?
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.58
Abstract: Introduction UK guidelines for LTx and HTx candidate referral require a minimum of 6 months abstinence from smoking and ALL forms of nicotine replacement before patients can be formally assessed. Our unit adopted this principle… read more here.
Keywords: htx; pos; htx candidates; cotinine ... See more keywords