DrTransformer: heuristic cotranscriptional RNA folding using the nearest neighbor energy model
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btad034
Abstract: Background Folding during transcription can have an important influence on the structure and function of ℝNA molecules, as regions closer to the 5’ end can fold into metastable structures before potentially stronger interactions with the… read more here.
Keywords: folding using; heuristic cotranscriptional; rna folding; transcription ... See more keywords
Distributed biotin–streptavidin transcription roadblocks for mapping cotranscriptional RNA folding
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx233
Abstract: Abstract RNA folding during transcription directs an order of folding that can determine RNA structure and function. However, the experimental study of cotranscriptional RNA folding has been limited by the lack of easily approachable methods… read more here.
Keywords: transcription; biotin streptavidin; rna; rna folding ... See more keywords