Effect of Protein Structure on Evolution of Cotranslational Folding.
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DOI: 10.1016/j.bpj.2020.06.037
Abstract: Cotranslational folding depends on the folding speed and stability of the nascent protein. It remains difficult, however, to predict which proteins cotranslationally fold. Here, we simulate evolution of model proteins to investigate how native structure… read more here.
Keywords: folding; contact; cotranslational folding; protein ... See more keywords
Cotranslational Folding of a Pentarepeat β-Helix Protein.
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DOI: 10.1016/j.jmb.2018.10.016
Abstract: It is becoming increasingly clear that many proteins start to fold cotranslationally before the entire polypeptide chain has been synthesized on the ribosome. One class of proteins that a priori would seem particularly prone to… read more here.
Keywords: pentarepeat; folding; cotranslational folding; helix protein ... See more keywords
Role of cotranslational folding for β-sheet-enriched proteins: A perspective from molecular dynamics simulations.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review. E"
DOI: 10.1103/physreve.105.024402
Abstract: The formations of correct three-dimensional structures of proteins are essential to their functions. Cotranslational folding is vital for proteins to form correct structures in vivo. Although some experiments have shown that cotranslational folding can improve… read more here.
Keywords: dynamics simulations; folding; cotranslational folding; sheet enriched ... See more keywords