K-Cl Cotransporter 2–mediated Cl− Extrusion Determines Developmental Stage–dependent Impact of Propofol Anesthesia on Dendritic Spines
Sign Up to like & getrecommendations! Published in 2017 at "Anesthesiology"
DOI: 10.1097/aln.0000000000001587
Abstract: Background: General anesthetics potentiating &ggr;-aminobutyric acid (GABA)–mediated signaling are known to induce a persistent decrement in excitatory synapse number in the cerebral cortex when applied during early postnatal development, while an opposite action is produced… read more here.
Keywords: propofol; cotransporter mediated; mediated inhibition; gabaa mediated ... See more keywords