Diversity of aging of the immune system classified in the cotton rat (Sigmodon hispidus) model of human infectious diseases
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2017.12.026
Abstract: ABSTRACT Susceptibility and declined resistance to human pathogens like respiratory syncytial virus (RSV) at old age is well represented in the cotton rat (Sigmodon hispidus). Despite providing a preferred model of human infectious diseases, little… read more here.
Keywords: age; cotton rat; rat sigmodon; immune system ... See more keywords
Preclinical evaluation of bacterially produced RSV-G protein vaccine: Strong protection against RSV challenge in cotton rat model
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep42428
Abstract: In current study, we evaluated the safety and protective efficacy of recombinant unglycosylated RSV G protein ectodomain produced in E. coli (in presence and absence of oil-in-water adjuvant) in a preclinical RSV susceptible cotton rat… read more here.
Keywords: protein; protein vaccine; rsv protein; cotton rat ... See more keywords
Compensatory mortality explains rodent resilience to an invasive predator
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Mammalogy"
DOI: 10.1093/jmammal/gyad043
Abstract: Invasive Burmese pythons (Python bivittatus) in the Everglades of Florida, United States, have drastically reduced populations of mammals, yet populations of some rodents appear unaffected by the invasion. To understand this pattern, we radio-tagged cotton… read more here.
Keywords: python occurrence; cotton; mortality; occurrence ... See more keywords
Cotton Rat Placenta Anatomy and Fc Receptor Expression and Their Roles in Maternal Antibody Transfer.
Sign Up to like & getrecommendations! Published in 2020 at "Comparative medicine"
DOI: 10.30802/aalas-cm-20-000040
Abstract: Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and viral pneumonia in infants and young childrenworldwide. Currently no vaccine is available to prevent RSV infection, but virus-neutralizing monoclonal antibodies can begiven prophylactically, emphasizing… read more here.
Keywords: cotton; anatomy; transfer; antibody ... See more keywords