Crystal structure of the Fusarium oxysporum tannase‐like feruloyl esterase FaeC in complex with p‐coumaric acid provides insight into ligand binding
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14615
Abstract: Feruloyl esterases (FAEs) hydrolyze the ester bonds between hydroxycinnamic acids and arabinose residues of plant cell walls and exhibit considerable diversity in terms of substrate specificity. Here, we report the crystal structure of an FAE… read more here.
Keywords: coumaric acid; structure; fusarium oxysporum; tannase like ... See more keywords
Discovery of Novel Tyrosine Ammonia Lyases for the Enzymatic Synthesis of p‐Coumaric Acid
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200062
Abstract: p‐Coumaric acid (p‐CA) is a key precursor for the biosynthesis of flavonoids. Tyrosine ammonia lyases (TALs) specifically catalyze the synthesis of p‐CA from l‐tyrosine, which is a convenient enzymatic pathway. To explore novel and highly… read more here.
Keywords: tyrosine ammonia; synthesis; coumaric acid; ammonia lyases ... See more keywords
Gastric healing effect of p-coumaric acid isolated from Baccharis dracunculifolia DC on animal model
Sign Up to like & getrecommendations! Published in 2020 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-020-01928-9
Abstract: The p -coumaric acid is a phenolic compound present in large quantities in the extract of Baccharis dracunculifolia DC, a Brazilian medicinal plant used to treat gastric ulcer. Given the necessity for finding new chemical… read more here.
Keywords: gastric healing; effect; model; coumaric acid ... See more keywords
Phenolic metabolism in the hornwort Anthoceros agrestis: 4-coumarate CoA ligase and 4-hydroxybenzoate CoA ligase
Sign Up to like & getrecommendations! Published in 2020 at "Plant Cell Reports"
DOI: 10.1007/s00299-020-02552-w
Abstract: 4-Coumarate coenzyme A ligase and 4-hydroxybenzoate coenzyme A ligase from the hornwort Anthoceros agrestis expressed in E. coli were characterized on biochemical and molecular levels and showed interesting substrate specificities. Acyl-activating enzymes are associated with… read more here.
Keywords: coa ligase; anthoceros agrestis; coumaric acid; acid ... See more keywords
Characterization of two new aromatic amino acid lyases from actinomycetes for highly efficient production of p-coumaric acid
Sign Up to like & getrecommendations! Published in 2020 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-020-02325-5
Abstract: p-Coumaric acid (p-CA) is a bioactive natural product and an important industrial material for pharmaceuticals and nutraceuticals. It can be synthesized from deamination of l-tyrosine by tyrosine ammonia lyase (TAL). In this work, we discovered… read more here.
Keywords: sas tal; amino acid; coumaric acid; sts tal ... See more keywords
The blood and mRNA levels of antioxidant-related factors in common carp (Cyprinus carpio) fed p-Coumaric acid
Sign Up to like & getrecommendations! Published in 2020 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-020-00894-6
Abstract: The natural antioxidants are well known for their antioxidative activity without side effects when compared to antibiotics. Hence, the present study aimed at evaluating p -Coumaric acid as an antioxidant additive on the blood and… read more here.
Keywords: blood mrna; common carp; mrna levels; coumaric acid ... See more keywords
Neuroprotective effect of p-coumaric acid in mice with cerebral ischemia reperfusion injuries
Sign Up to like & getrecommendations! Published in 2018 at "Metabolic Brain Disease"
DOI: 10.1007/s11011-018-0185-7
Abstract: Cerebral ischemia reperfusion (IR) is associated with neuronal death, which leads to disability and cognitive decline. The pathomechanism occurs because ischemia is exacerbated during the reperfusion period. Neuronal damage susceptibility depends on the affected brain… read more here.
Keywords: reperfusion; coumaric acid; brain; cerebral ischemia ... See more keywords
Millets: a cereal grain with potent antioxidants and health benefits
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Food Measurement and Characterization"
DOI: 10.1007/s11694-018-9992-0
Abstract: Millet grains are small seeded Kharif crop used as food and feed. Due to presence of bioactive compounds and important minerals, millets have their own importance among cereal grains. Finger millet is a mixture of… read more here.
Keywords: millet; gallic acid; hydroxybenzoic acid; acid 100 ... See more keywords
Action of ultraviolet-C radiation and p-coumaric acid on stilbene accumulation and expression of stilbene biosynthesis-related genes in the grapevine Vitis amurensis Rupr.
Sign Up to like & getrecommendations! Published in 2019 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-019-2818-9
Abstract: This paper investigated the effects of p-coumaric acid (CA) on stilbene biosynthesis in healthy cuttings of grapevine Vitis amurensis Rupr. under control conditions and after ultraviolet (UV-C) irradiation. It has been shown that the content… read more here.
Keywords: grapevine vitis; stilbene biosynthesis; acid stilbene; coumaric acid ... See more keywords
p-Coumaric acid inhibits the Listeria monocytogenes RecA protein functions and SOS response: An antimicrobial target.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.07.093
Abstract: Bacterial RecA plays an important role in the evaluation of antibiotic resistance via stress-induced DNA repair mechanism; SOS response. Accordingly, RecA became an important therapeutic target against antimicrobial resistance. Small molecule inhibitors of RecA may… read more here.
Keywords: response; sos response; coumaric acid; resistance ... See more keywords
Local administration of p-coumaric acid decreases lipopolysaccharide-induced acute lung injury in mice: in vitro and in silico studies.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.173929
Abstract: Acute lung injury (ALI) remains to cause a high rate of mortality in critically ill patients. It is known that inflammation is a key factor in the pathogenesis of lipopolysaccharide (LPS)-induced ALI, which makes it… read more here.
Keywords: coumaric acid; mice; vitro; lung injury ... See more keywords