Reaction Course Dependent Regiospecific Transformation of 4‐Azido‐Coumarin into Coumarin C3‐C4 Fused Imidazole and 5‐Substituted‐1,4‐Benzodiazepine Scaffolds
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.202400575
Abstract: Herein, we report an efficient route for coumarin C3‐C4 fused imidazole scaffolds via indium chloride‐mediated single‐step transformation of 4‐azido‐coumarin with amines/aldehydes and coumarin C3‐C4 fused 5‐substituted‐1,4‐benzodiazepine scaffolds with 1,2‐azide‐nitrogen migration through two‐step sequential synthesis via the transitory intermediacy… read more here.
Keywords: azido coumarin; fused imidazole; coumarin fused; coumarin ... See more keywords
Fluorogenic "Photoclick" Labeling and Imaging of DNA with Coumarin-Fused Tetrazole in Vivo.
Sign Up to like & getrecommendations! Published in 2019 at "ACS sensors"
DOI: 10.1021/acssensors.8b00565
Abstract: Photoclickable fluorogenic probes will enable visualization of specific biomolecules with precise spatiotemporal control in their native environment. However, the fluorogenic tagging of DNA with current photocontrolled clickable probes is still challenging. Herein, we demonstrated the… read more here.
Keywords: fused tetrazole; imaging dna; vivo; labeling imaging ... See more keywords
A Ru(II)-Catalyzed C–H Activation and Annulation Cascade for the Construction of Highly Coumarin-fused Benzo[a]quinolizin-4-ones and Pyridin-2-ones
Sign Up to like & getrecommendations! Published in 2023 at "Organic Chemistry Frontiers"
DOI: 10.1039/d3qo00255a
Abstract: A Ru(II)-catalyzed C–H activation and annulation cascade were successfully established for the constructions of coumarin-fused benzo[a]quinolizin-4-ones and pyridin-2-ones, in which the intriguing 6-6-6-6-6 pentacyclic coumarin-fused scaffold was formed by a... read more here.
Keywords: annulation cascade; fused benzo; catalyzed activation; coumarin fused ... See more keywords